1,7,7-trimethylbicyclo<2.2.1>hept-2-ene-2-carboxylic acid | 861599-49-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1,7,7-trimethylbicyclo<2.2.1>hept-2-ene-2-carboxylic acid
• 英文别名: 1,7,7-trimethyl-norborn-2-ene-2-carboxylic acid；1,7,7-Trimethyl-norborn-2-en-2-carbonsaeure；1,7,7-Trimethylbicyclo[2.2.1]hept-2-ene-2-carboxylic acid
• CAS: 861599-49-7
• 化学式: C₁₁H₁₆O₂
• 分子量: 180.247
• InChiKey: CABLREOMPWLPLF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,7,7-trimethylbicyclo<2.2.1>hept-2-ene-2-carboxylic acid 在 氯化亚砜 作用下， 生成 N-formyl-N,1,7,7-tetramethylbicyclo[2.2.1]hept-2-ene-2-carboxamide
  参考文献：
  名称：

  Photochemistry of aliphatic imides. Synthesis of azetidine-2,4-diones via photochemical isomerization of succinimides and N-formyl-N-methyl .alpha.,.beta.-unsaturated amides

  摘要：

  DOI：

  10.1021/jo00314a006
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 1,7,7-trimethylbicyclo<2.2.1>hept-2-ene-2-carboxylic acid
  参考文献：
  名称：

  Bredt; Perkin, Journal of the Chemical Society, 1913, vol. 103, p. 2224

  摘要：

  DOI：

文献信息

• Synthesis of bornene-2,2′-diamino-1,1′-binaphthalene conjugates in palladium-catalysed aminocarbonylations
  作者：Gábor Mikle、Borbála Boros、László Kollár

  DOI：10.1016/j.tetasy.2016.03.010

  日期：2016.6

  Palladium-catalysed aminocarbonylation of a terpenoic iodoalkene (2-iodo-bornene) model compound with both enantiomerically pure and racemic 2,2'-diamino-1,1'-binaphthalene (BINAM) as the N-nucleophile was carried out. All of the diastereoisomers of the monocarboxamide (N-bornenyl carboxamide) and dicarboxamide (N,N'-dinorbomenylcarboxamide) derivatives were synthesised. The diastereoselectivities of the aminocarbonylation were investigated in both cases: either racemic BINAM was used as the N-nucleophile in the aminocarbonylation of enantiomerically pure 2-iodobornene or racemic iodobornene was aminocarbonylated with enantiomerically pure BINAM with moderate diastereoselectivities. In this way, all possible diastereoisomers of binaphthalene-bornene conjugates were synthesised in moderate to high yields by asymmetric (diastereoselective) aminocarbonylation. (C) 2016 Elsevier Ltd. All rights reserved.
• Passerini, Gazzetta Chimica Italiana, 1924, vol. 54, p. 534
  作者：Passerini

  DOI：——

  日期：——
• Photochemistry of aliphatic imides. Synthesis of azetidine-2,4-diones via photochemical isomerization of succinimides and N-formyl-N-methyl .alpha.,.beta.-unsaturated amides
  作者：Kazuhiro Maruyama、Takeshi Ishitoku、Yasuo Kubo

  DOI：10.1021/jo00314a006

  日期：1981.1
• Bredt; Perkin, Journal of the Chemical Society, 1913, vol. 103, p. 2224
  作者：Bredt、Perkin

  DOI：——

  日期：——