1-Phenoxy-4-(o-kresyloxy)butan | 68720-26-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-Phenoxy-4-(o-kresyloxy)butan
• 英文别名: 1-Methyl-2-(4-phenoxybutoxy)benzene
• CAS: 68720-26-3
• 化学式: C₁₇H₂₀O₂
• 分子量: 256.345
• InChiKey: TVBLBKFERAKVBT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  邻甲酚 生成 1-Phenoxy-4-(o-kresyloxy)butan
  参考文献：
  名称：

  PAL RAM SEWAK; BOKADIA MISHRI MAL., POL. J. CHEM., 1978, 52, NO 7-8, 1473-1477

  摘要：

  DOI：

文献信息

• AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF
  申请人：Ogura Hironobu

  公开号：US20100190754A1

  公开（公告）日：2010-07-29

  An azolylmethylidenehydrazine derivative represented by the formula (I) wherein Ar is an aryl group optionally having substituent(s) or a heteroaryl group optionally having substituent(s), R 1 and R 2 are the same or different and each is an alkyl group, a cycloalkyl group, an aralkyl group optionally having substituent(s), an aryl group optionally having substituent(s), a heteroarylalkyl group optionally having substituent(s), or R 1 and R 2 are bonded to each other to form a nitrogen-containing heterocyclic group optionally having substituent(s), and X is CH or a nitrogen atom, or a pharmacologically acceptable salt thereof is useful as a medicament, particularly as an antifungal agent, or an anti-inflammatory agent or an antiallergic agent.

  一种以式(I)表示的氮杂环甲基亚唑啉衍生物，其中Ar是一个芳基基团，可选择地具有取代基，或者是一个杂芳基基团，可选择地具有取代基；R1和R2相同或不同，每个都是一个烷基基团、环烷基基团、可选择地具有取代基的芳基烷基基团、可选择地具有取代基的芳基基团、可选择地具有取代基的杂芳基烷基基团，或者R1和R2彼此连接形成一个可选择地具有取代基的含氮杂环基团；X是CH或氮原子；或其药学上可接受的盐，可用作药物，特别是作为抗真菌药物、抗炎药物或抗过敏药物。
• AZOLYLMETHYLENEHYDRAZINE DERIVATIVE AND USE THEREOF
  申请人：KAKEN PHARMACEUTICAL CO., LTD.

  公开号：EP2168951A1

  公开（公告）日：2010-03-31

  An azolylmethylidenehydrazine derivative represented by the formula (I) wherein Ar is an aryl group optionally having substituent(s), a heteroaryl group optionally having substituent(s) or a heteroaryl group optionally having substituent(s), R1 and R2 are the same or different and each is an alkyl group, a cycloalkyl group, an aralkyl group optionally having substituent(s), an aryl group optionally having substituent(s), a heteroarylalkyl group optionally having substituent(s), or R1 and R2 are bonded to each other to form a nitrogen-containing heterocyclic group optionally having substituent(s), and X is CH or a nitrogen atom, or a pharmacologically acceptable salt thereof is useful as a medicament, particularly as an antifungal agent, or an anti-inflammatory agent or an antiallergic agent.

  由式 (I) 代表的偶氮亚甲基肼衍生物 其中 Ar 是可选具有取代基的芳基、可选具有取代基的杂芳基或可选具有取代基的杂芳基、 R1 和 R2 相同或不同，且各自为烷基、环烷基、任选具有取代基的芳烷基、任选具有取代基的芳基、任选具有取代基的杂芳基，或 R1 和 R2 相互键合形成任选具有取代基的含氮杂环基，且 X 为 CH 或氮原子、 或其药理上可接受的盐可用作药物，特别是抗真菌剂、抗炎剂或抗过敏剂。
• Pal,R.S.; Bokadia,M.M., Polish Journal of Chemistry, 1978, vol. 52, p. 1473 - 1477
  作者：Pal,R.S.、Bokadia,M.M.

  DOI：——

  日期：——
• US8022072B2
  申请人：——

  公开号：US8022072B2

  公开（公告）日：2011-09-20
• PAL RAM SEWAK; BOKADIA MISHRI MAL., POL. J. CHEM., 1978, 52, NO 7-8, 1473-1477
  作者：PAL RAM SEWAK、 BOKADIA MISHRI MAL.

  DOI：——

  日期：——