1-triphenylsiloxy-propane-3-thiol | 205698-60-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-triphenylsiloxy-propane-3-thiol
• 英文别名: trimethyl-hydroxyl silylated thiol；3-Triphenylsilyloxypropane-1-thiol
• CAS: 205698-60-8
• 化学式: C₂₁H₂₂OSSi
• 分子量: 350.557
• InChiKey: ZJMGNCODHMPTCQ-UHFFFAOYSA-N

物化性质

• 沸点：
  410.0±28.0 °C(Predicted)
• 密度：
  1.11±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.99
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  10.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  tetra-n-butylammonium tetrachlorooxorhenate(V) 、 2-(diphenylphosphanyl)-N-(2-thioethyl)benzamide 、 1-triphenylsiloxy-propane-3-thiol 在 triethylamine 作用下， 以 二氯甲烷 为溶剂， 以34%的产率得到[Re(O)(κ3-PNS)(κ1-S-CH2CH2CH2OSi(phenyl)3]
  参考文献：
  名称：

  Silylated mixed-ligand rhenium complexes with the [PNS/S] donor atom set

  摘要：

  New oxorhenium complexes with 2-(diphenylphosphanyl)-N-(2-thioethyl)benzamide (HPNS) and trimethyl-, triethyl- and triphenyl-hydroxyl silylated monodentate thiols are reported. These new complexes have been prepared by reacting [(NBu4)-Bu-n][Re(O)Cl-4] with the tridentate HPNS and the corresponding silylated thiol at room temperature. The characterization of the complexes involved elemental analysis, P-31 and H-1 NMR spectroscopies and X-ray crystallographic analysis for the triethyl-silylated Re complex. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(02)01486-x
• 作为产物：
  描述：

  3-巯基-1-丙醇 、 三苯基氯硅烷 在 咪唑 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以68%的产率得到1-triphenylsiloxy-propane-3-thiol
  参考文献：
  名称：

  Synthesis of hydroxyl silylated rhenium and (99mTc)technetium ?3+1? mixed ligand complexes

  摘要：

  本文介绍了羟基硅烷化硫醇作为单齿配体的合成过程。以 3thiapentane-1,5-dithiol 作为辅助配体，这些单齿配体被用于与 Re 和 99mTc 三甲基、三乙基和三苯基硅烷化 "3+1 "混合配体复合物的构建。Re 复合物通过 1H NMR 和元素分析进行表征，99mTc 复合物通过无线电 HPLC 进行检测。三甲基硅烷基化衍生物在水介质中会水解，而三乙基和三苯基硅烷基化复合物在中性溶液中证明是稳定的。Copyright © 2002 John Wiley & Sons, Ltd. All Rights Reserved.

  DOI：

  10.1002/jlcr.567

文献信息

• Synthesis of hydroxyl silylated rhenium and (99mTc)technetium ?3+1? mixed ligand complexes
  作者：Torsten Kniess、Hartmut Spies、Isabel Santos、Alla Zablotska

  DOI：10.1002/jlcr.567

  日期：2002.7

  The synthesis of hydroxyl silylated thiols as monodentate ligands is described. These monodentates were used to build with Re and 99mTc trimethyl-, triethyl- and triphenyl-silylated ‘3+1’ mixed ligand complexes, using 3thiapentane-1,5-dithiol as co-ligand. The Re complexes were characterized by 1H NMR and elemental analysis, the 99mTc complexes were detected by radio HPLC. While the trimethyl silylated derivatives hydrolysed in aqueous media, the triethyl- and triphenyl silylated complexes have proved to be stable in neutral solutions. Copyright © 2002 John Wiley & Sons, Ltd.

  本文介绍了羟基硅烷化硫醇作为单齿配体的合成过程。以 3thiapentane-1,5-dithiol 作为辅助配体，这些单齿配体被用于与 Re 和 99mTc 三甲基、三乙基和三苯基硅烷化 "3+1 "混合配体复合物的构建。Re 复合物通过 1H NMR 和元素分析进行表征，99mTc 复合物通过无线电 HPLC 进行检测。三甲基硅烷基化衍生物在水介质中会水解，而三乙基和三苯基硅烷基化复合物在中性溶液中证明是稳定的。Copyright © 2002 John Wiley & Sons, Ltd. All Rights Reserved.
• Silylated mixed-ligand rhenium complexes with the [PNS/S] donor atom set
  作者：Torsten Kniess、Celia Fernandes、Isabel Santos、Werner Kraus、Hartmut Spies

  DOI：10.1016/s0020-1693(02)01486-x

  日期：2003.5

  New oxorhenium complexes with 2-(diphenylphosphanyl)-N-(2-thioethyl)benzamide (HPNS) and trimethyl-, triethyl- and triphenyl-hydroxyl silylated monodentate thiols are reported. These new complexes have been prepared by reacting [(NBu4)-Bu-n][Re(O)Cl-4] with the tridentate HPNS and the corresponding silylated thiol at room temperature. The characterization of the complexes involved elemental analysis, P-31 and H-1 NMR spectroscopies and X-ray crystallographic analysis for the triethyl-silylated Re complex. (C) 2002 Elsevier Science B.V. All rights reserved.