perfluoro[1,4-bis(fluorocarbonylmethyl)-1,4-piperazine] | 250688-31-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: perfluoro[1,4-bis(fluorocarbonylmethyl)-1,4-piperazine]
• 英文别名: Perfluoro-1,4-bis(fluorocarbonylmethyl)piperazine；2,2-Difluoro-2-[2,2,3,3,5,5,6,6-octafluoro-4-(1,1,2-trifluoro-2-oxoethyl)piperazin-1-yl]acetyl fluoride
• CAS: 250688-31-4
• 化学式: C₈F₁₄N₂O₂
• 分子量: 422.078
• InChiKey: XLJWHUGDEUSHDO-UHFFFAOYSA-N

物化性质

• 沸点：
  166.6±40.0 °C(Predicted)
• 密度：
  1.89±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  40.6
• 氢给体数：
  0
• 氢受体数：
  18

反应信息

• 作为反应物：
  描述：

  甲醇 、 perfluoro[1,4-bis(fluorocarbonylmethyl)-1,4-piperazine] 生成 1,4-Bis(methoxycarbonyldifluoromethyl)octafluoropiperazine
  参考文献：
  名称：

  二和三（2-羟乙基）取代的烷基胺的电化学氟化

  摘要：

  几种2-（羟乙基）取代的烷基胺，例如1,4-双（2-羟乙基）哌嗪，N，N-双（2-羟乙基）甲胺，N，N-双（2-羟乙基）乙胺和N，N对N-三（2-羟乙基）胺及其衍生物（HCl盐，硼酸盐和三甲基甲硅烷基醚）进行电化学氟化。从1，4-双（2-羟乙基）哌嗪，以低收率获得F- [1，4-双（氟羰基甲基）哌嗪]。在N，N-双（2-羟乙基）烷基胺和N，N，N的氟化中-三（2-羟乙基）胺，广泛发生环化反应，提供了大量的F-吗啉衍生物。然而，从前者以低的，分离的产率获得了F - N，N-双（氟羰基甲基）甲胺。

  DOI：

  10.1016/s0022-1139(99)00106-2
• 作为产物：
  描述：

  1,4-双(2-羟基乙基)哌嗪 在 氢氟酸 作用下， 反应 10.62h， 以5.9%的产率得到perfluoro(4-methylpiperazin-1-ylacetyl fluoride)
  参考文献：
  名称：

  二和三（2-羟乙基）取代的烷基胺的电化学氟化

  摘要：

  几种2-（羟乙基）取代的烷基胺，例如1,4-双（2-羟乙基）哌嗪，N，N-双（2-羟乙基）甲胺，N，N-双（2-羟乙基）乙胺和N，N对N-三（2-羟乙基）胺及其衍生物（HCl盐，硼酸盐和三甲基甲硅烷基醚）进行电化学氟化。从1，4-双（2-羟乙基）哌嗪，以低收率获得F- [1，4-双（氟羰基甲基）哌嗪]。在N，N-双（2-羟乙基）烷基胺和N，N，N的氟化中-三（2-羟乙基）胺，广泛发生环化反应，提供了大量的F-吗啉衍生物。然而，从前者以低的，分离的产率获得了F - N，N-双（氟羰基甲基）甲胺。

  DOI：

  10.1016/s0022-1139(99)00106-2

文献信息

• NITROGEN-CONTAINING FLUOROKETONES FOR HIGH TEMPERATURE HEAT TRANSFER
  申请人：FLYNN Richard M.

  公开号：US20110232870A1

  公开（公告）日：2011-09-29

  Nitrogen-containing fluorochemical ketones are provided that can be useful in apparatuses that includes a device and a mechanism for transferring heat. The provided fluorochemical ketones are stable at temperatures above 170° C., are environmentally friendly, and are economical to produce. The provided apparatuses can be useful for vapor phase soldering of electronic devices.

  提供含氮氟化学酮，可用于包括传热机制的装置中。提供的氟化学酮在高于170°C的温度下稳定，环保且经济实惠。提供的装置可用于电子设备的蒸气相焊接。
• Simons electrochemical fluorination of substituted homopiperazines(hexahydro-1,4-diazepines) and piperazines
  作者：Takashi Abe、Hajime Baba、Haruhiko Fukaya、Masanori Tamura、Akira Sekiya

  DOI：10.1016/s0022-1139(02)00247-6

  日期：2003.1

  Simons electrochemical fluorination (ECF) of 1,4-dimethyl-1,4-homopiperazine, methyl 4-ethylhomopiperazin-1-ylacetate and 1, 4-bis(methoxycarbonylmethyl)-1,4-homopiperazine was studied. For comparison, ECF of three piperazines with a N-(methoxycarbonylmethyl) group(s) was also studied. ECF of 1,4-dimethyl-1,4-homopiperazine gave a low yield of corresponding perfluoro(1,4dimethyl-1,4-homopiperazine) together with perfluoro(2,6-diaza-2,6-dimethylheptane) as the major product. Corresponding perfluoro(homopiperazines) with mono- and/or di-(fluorocarbonyldifluoromethyl) groups [-CF2C(O)F] at the 1- and/or 4-position were formed in low yields from methyl 4-ethylhomopiperazin-1-ylacetate and 1,4-bis(methoxycarbonylmethyl)-1,4-homopiperazine, respectively. These new seven-membered perfluoro(1,4-dialkyl-1,4-homopiperazines) were accompanied by the formation of mono- and/or di-basic linear perfluoroacid fluorides resulting from the C-C bond scission at the 2- and 3-positions of the ring. From mono- and/or di-N-(methoxycarbonylmethyl)-substituted piperazines, corresponding perfluoropeperazines having the acid fluoride group(s) were formed in low yields. (C) 2002 Elsevier Science B.V. All rights reserved.
• JP2000086643A
  申请人：——

  公开号：JP2000086643A

  公开（公告）日：2000-03-28
• US8535559B2
  申请人：——

  公开号：US8535559B2

  公开（公告）日：2013-09-17
• [EN] NITROGEN-CONTAINING FLUOROKETONES FOR HIGH TEMPERATURE HEAT TRANSFER<br/>[FR] FLUOROCÉTONES AZOTÉES DESTINÉES AU TRANSFERT DE CHALEUR À HAUTE TEMPÉRATURE
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2011119456A1

  公开（公告）日：2011-09-29

  Nitrogen-containing fluorochemical ketones are provided that can be useful in apparatuses that includes a device and a mechanism for transferring heat. The provided fluorochemical ketones are stable at temperatures above 170°C, are environmentally friendly, and are economical to produce. The provided apparatuses can be useful for vapor phase soldering of electronic devices.