4-(2-propenyloxymethyl)-2-(p-chlorophenyl)-1,3-dioxolane | 388566-49-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(2-propenyloxymethyl)-2-(p-chlorophenyl)-1,3-dioxolane
• 英文别名: 2-(4-chlorophenyl)-4-(prop-2-enoxymethyl)-1,3-dioxolane
• CAS: 388566-49-2
• 化学式: C₁₃H₁₅ClO₃
• 分子量: 254.713
• InChiKey: BPIMUDWIBMXRGS-UHFFFAOYSA-N

物化性质

• 沸点：
  355.5±42.0 °C(Predicted)
• 密度：
  1.163±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(2-propenyloxymethyl)-2-(p-chlorophenyl)-1,3-dioxolane 在 溴 作用下， 以 氯仿 为溶剂， 以64%的产率得到4-(2,3-dibromopropoxymethyl)-2-(p-chlorophenyl)-1,3-dioxolane
  参考文献：
  名称：

  摘要：

  2,4-Disubstituted 1,3-dioxolanes were synthesized by reactions of benzaldehyde and its parachloro derivatives, as well as 3-cyclohexenecarboxaldehyde with 3-(2-propenyloxy)-1,2-propanediol. The products were brought into bromination, dichlorocarbene addition, and epoxidation reactions. It is found that when both components of the heterogeneous reaction of dioxolane ring formation have a double bond, the acid catalyst in strongly deactivated.

  DOI：

  10.1023/a:1012379001179
• 作为产物：
  描述：

  甘油烯丙基醚 、 4-氯苯甲醛 在 KU-2 cation exchanger (H⁺ form) 作用下， 以 甲苯 为溶剂， 反应 5.0h， 以82%的产率得到4-(2-propenyloxymethyl)-2-(p-chlorophenyl)-1,3-dioxolane
  参考文献：
  名称：

  摘要：

  2,4-Disubstituted 1,3-dioxolanes were synthesized by reactions of benzaldehyde and its parachloro derivatives, as well as 3-cyclohexenecarboxaldehyde with 3-(2-propenyloxy)-1,2-propanediol. The products were brought into bromination, dichlorocarbene addition, and epoxidation reactions. It is found that when both components of the heterogeneous reaction of dioxolane ring formation have a double bond, the acid catalyst in strongly deactivated.

  DOI：

  10.1023/a:1012379001179

文献信息

• ——
  作者：A. Kh. Kerimov

  DOI：10.1023/a:1012379001179

  日期：——

  2,4-Disubstituted 1,3-dioxolanes were synthesized by reactions of benzaldehyde and its parachloro derivatives, as well as 3-cyclohexenecarboxaldehyde with 3-(2-propenyloxy)-1,2-propanediol. The products were brought into bromination, dichlorocarbene addition, and epoxidation reactions. It is found that when both components of the heterogeneous reaction of dioxolane ring formation have a double bond, the acid catalyst in strongly deactivated.