5,5'-dibromo-N,N'-di(n-butylpropionato)-2,2'-biimidazole | 1352957-42-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 5,5'-dibromo-N,N'-di(n-butylpropionato)-2,2'-biimidazole
• 英文别名: Butyl 3-[5-bromo-2-[5-bromo-1-(3-butoxy-3-oxopropyl)imidazol-2-yl]imidazol-1-yl]propanoate；butyl 3-[5-bromo-2-[5-bromo-1-(3-butoxy-3-oxopropyl)imidazol-2-yl]imidazol-1-yl]propanoate
• CAS: 1352957-42-6
• 化学式: C₂₀H₂₈Br₂N₄O₄
• 分子量: 548.275
• InChiKey: KBJYTNYDJRIPDC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  30
• 可旋转键数：
  15
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  88.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  Di-tert-butyl 3,3'-(2,2'-bi-1H-imidazole-1,1'-diyl)dipropanoate 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 氯仿 为溶剂， 反应 2.0h， 以67%的产率得到5,5'-dibromo-N,N'-di(n-butylpropionato)-2,2'-biimidazole
  参考文献：
  名称：

  Conjugated polymers containing a 2,2′-biimidazole moiety—a novel fluorescent sensing platform

  摘要：

  我们设计、合成并展示了两种含有 2,2â²-双咪唑分子的新型共轭聚合物，它们可用作检测 Ag+ 和半胱氨酸的有效荧光传感平台。这是首个利用荧光共轭聚合物-Ag+复合物选择性检测半胱氨酸的实例，检测限为纳摩尔范围。

  DOI：

  10.1039/c1cc15787f

文献信息

• 2,2′-Biimidazole-Based Conjugated Polymers as a Novel Fluorescent Sensing Platform for Pyrophosphate Anion
  作者：Yinyin Bao、Hu Wang、Qianbiao Li、Bin Liu、Qing Li、Wei Bai、Bangkun Jin、Ruke Bai

  DOI：10.1021/ma300361t

  日期：2012.4.24

  Three novel conjugated polymers based on 2,2'-biimidazole have been successfully designed and synthesized through the Suzuki coupling reactions, and their fluorescence sensing ability to metal ions and anions was investigated. The emission of the two polymers with hydrophilic side chains can be efficiently quenched by Cu2+ through a photoinduced electron transfer process. Moreover, the polymer Cu2+ complexes exhibit excellent "turn on" sensing properties for detection of pyrophosphate (PP anion. These complex sensors possess high selectivity avoiding the interference from other anions, very fast response (less than 3 min) to PPi, and the detection limit of about 0.17 ppm. In addition, the linear detection range of PPi can be tuned conveniently by changing the amount of Cu2+ ions. Thus, the conjugated polymers can be used as a novel fluorescent sensing platform, and this work provides a new strategy for the development of PPi sensors.