4-(decylthio)benzaldehyde | 157376-04-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(decylthio)benzaldehyde
• 英文别名: 4-Decylsulfanylbenzaldehyde
• CAS: 157376-04-0
• 化学式: C₁₇H₂₆OS
• mdl: MFCD26359042
• 分子量: 278.459
• InChiKey: FPTLOSKTPMCMLR-UHFFFAOYSA-N

物化性质

• 沸点：
  399.2±25.0 °C(predicted)
• 密度：
  0.99±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  19
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.588
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-(decylthio)benzaldehyde 在 lithium aluminium tetrahydride 、 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 反应 5.0h， 生成 [4-[(E)-2-(4-decylsulfanylphenyl)ethenyl]phenyl]methanol
  参考文献：
  名称：

  Synthesis and optical characterization of unsymmetrical oligophenylenevinylenes

  摘要：

  An efficient route to highly soluble unsymmetrical oligo(phenylenevinylenes) (OPVs) has been developed. The OPVs are end-substituted with donor alkoxy and acceptor sulfonyl groups for charge polarization and incorporate a methacrylate unit suitable for co-polymerization. The absorption and excitation spectra of the OPVs and their precursors have been examined; vibronic features are noted, and pi-system lengthening and introduction of polarizing substituents red-shift the spectral maxima. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(02)00003-0
• 作为产物：
  描述：

  1-癸硫醇 、 对氟苯甲醛 在 sodium carbonate 作用下， 以 二甲基亚砜 为溶剂， 以92%的产率得到4-(decylthio)benzaldehyde
  参考文献：
  名称：

  Synthesis and optical characterization of unsymmetrical oligophenylenevinylenes

  摘要：

  An efficient route to highly soluble unsymmetrical oligo(phenylenevinylenes) (OPVs) has been developed. The OPVs are end-substituted with donor alkoxy and acceptor sulfonyl groups for charge polarization and incorporate a methacrylate unit suitable for co-polymerization. The absorption and excitation spectra of the OPVs and their precursors have been examined; vibronic features are noted, and pi-system lengthening and introduction of polarizing substituents red-shift the spectral maxima. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(02)00003-0

文献信息

• Synthesis and properties of highly soluble third-order optically nonlinear chromophores and methacrylate monomer based on distyrylbenzene
  作者：M. S. Wong、M. Samoc、A. Samoc、B. Luther-davies、M. G. Humphrey

  DOI：10.1039/a803229g

  日期：——

  A novel series of highly soluble distyrylbenzenes bearing poly(alkyleneoxy) and/or alkylsulfonyl solubilizing substituents has been synthesized using the stereoselective Wadsworth–Emmons reaction as a key step. The corresponding poly(alkyleneoxy) alkylsulfonyl 4,4′-disubstituted distyrylbenzene has been covalently incorporated into an acrylic monomer which has also been successfully co-polymerized with methyl methacrylate (MMA). All the 4,4′-disubstituted distyrylbenzenes and the polyacrylate based co-polymer show excellent solubility, processibility and thermal stability. Importantly, 2-(2-butoxyethoxy)ethoxy-hexylsulfonyl 4,4′-disubstituted distyrylbenzene exhibits only a minor bathochromic shift of the absorption maximum compared to those of the corresponding symmetrically 4,4′-disubstituted distyrylbenzenes; however, its third-order optical nonlinearity derived from Z-scan measurements at 800 nm is approximately twice as large as those of its symmetrically 4,4′-disubstituted counterparts.

  以立体选择性 Wadsworth-Emmons 反应为关键步骤，合成了一系列新型高溶解性二丙烯苯，这些二丙烯苯带有聚（烷氧基）和/或烷基磺酰基增溶取代基。相应的 4,4′-二取代二丙烯酰基聚（烷氧基）烷基磺酰基已与丙烯酸单体共价结合，并成功地与甲基丙烯酸甲酯（MMA）共聚。所有 4,4′-二取代二丙烯酰苯和基于聚丙烯酸酯的共聚物都表现出优异的溶解性、加工性和热稳定性。重要的是，与相应的对称 4,4′-二取代二丙烯苯相比，2-（2-丁氧基乙氧基）乙氧基-己基磺酰基 4,4′-二取代二丙烯苯的吸收最大值仅有轻微的浴色偏移；然而，在 800 纳米波长处通过 Z 扫描测量得出的三阶光学非线性大约是对称的 4,4′-二取代二丙烯苯的两倍。
• Derivatives of cyclic peptide nuclei
  申请人：ELI LILLY AND COMPANY

  公开号：EP0031220A1

  公开（公告）日：1981-07-01

  Compounds of the formula wherein R1 is H or OH and; when R1 is H, R2 is H and R3 and R4 are both H or both OH, and when R' is OH, R2 is H, R3 is OH or C1-C8 alkyloxy and R4 is OH, or R2 is -CO-NH2 and R3 and R4 are both OH, and wherein R6 is a group of the formula : or wherein A is divalent oxygen, sulfur, sulfinyl, or sulfonyl; A' is divaleat oxygen, sulfur, sulfinyl, sulfonyl or -NH-; X is hydrogen, chloro, bromo, iodo, nitro, C1-C3 alkyl, hydroxy, C1-C3 alkoxy, mercapto, C1-C3 alkylthio, carbamyl or C1-C3 alkylcarbamyl ; X' is chloro, bromo or iodo; R6 is hydrogen C1-C18 alkyl or C2-C18 alkenyl; W is C1-C10 alkylene or C2-C10 alkenylene; m, n and p are 0 or 1, but if m = 0, n must = 0; provided: that the sum of the carbon atoms in the R6 and W groups must be greater than 4 but cannot exceed 21; that when X is mercapto, A and A1 cannot be sulfinyl or sulfonyl and that when A and A1 are sulfinyl or sulfonyl, they must be in equal oxidation states, have antifungal activity.

  式中的化合物 其中 R1 是 H 或 OH 并且 当 R1 是 H 时，R2 是 H，R3 和 R4 都是 H 或都是 OH，以及 当 R' 为 OH 时，R2 为 H，R3 为 OH 或 C1-C8 烷氧基，R4 为 OH，或 R2 为 -CO-NH2 且 R3 和 R4 均为 OH，以及 其中 R6 为式： 或 其中 A 是二价氧、硫、亚砜基或磺酰基；A'是二价氧、硫、亚砜基、磺酰基或 -NH-；X 是氢、氯、溴、碘、硝基、C1-C3 烷基、羟基、C1-C3 烷氧基、巯基、C1-C3 烷硫基、羰基或 C1-C3 烷基羰基；X' 是氯、溴或碘； R6 是氢 C1-C18 烷基或 C2-C18 烯基； W 是 C1-C10 亚烷基或 C2-C10 烯基； m、n 和 p 是 0 或 1，但如果 m = 0，则 n 必须 = 0；前提是R6 和 W 基团中碳原子的总和必须大于 4，但不能超过 21；当 X 为巯基时，A 和 A1 不能为亚磺酰基或磺酰基，当 A 和 A1 为亚磺酰基或磺酰基时，它们必须处于相等的氧化态，具有抗真菌活性。
• US4293486A
  申请人：——

  公开号：US4293486A

  公开（公告）日：1981-10-06
• US4289692A
  申请人：——

  公开号：US4289692A

  公开（公告）日：1981-09-15
• US4293484A
  申请人：——

  公开号：US4293484A

  公开（公告）日：1981-10-06