trans-1,2-dibutylcyclopropane | 72149-16-7

• 分子结构分类: 有机化合物 - 碳氢化合物 - 饱和烃
• 英文名称: trans-1,2-dibutylcyclopropane
• 英文别名: trans-5,6-methylenedecane；(1R,2R)-1,2-Dibutylcyclopropane
• CAS: 72149-16-7
• 化学式: C₁₁H₂₂
• 分子量: 154.296
• InChiKey: NFTQIMBYKJVJIT-GHMZBOCLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  反-5-癸烯 、 alkaline earth salt of/the/ methylsulfuric acid 以 1,4-二氧六环 为溶剂， 反应 12.0h， 生成 trans-1,2-dibutylcyclopropane
  参考文献：
  名称：

  (.eta.5-C5H5)(CO)2FeCH2S+(CH3)2 BF4-: a methylene transfer reagent for the direct cyclopropanation of alkenes

  摘要：

  DOI：

  10.1021/ja00246a036

文献信息

• Gai, Yonghua; Julia, Marc; Verpeaux, Jean-Noel, Bulletin de la Societe Chimique de France, 1996, vol. 133, # 9, p. 817 - 829
  作者：Gai, Yonghua、Julia, Marc、Verpeaux, Jean-Noel

  DOI：——

  日期：——
• Mechanism-Based Design and Optimization of a Catalytic Electrophilic Cyclopropanation without Diazomethane
  作者：Augustin A. S. W. Tchawou、Mihai Raducan、Peter Chen

  DOI：10.1021/acs.organomet.6b00531

  日期：2017.1.9

  Iodomethylboron compounds, either the trifluoroborate or a boronic ester, cyclopropanate electron-rich olefins and unprotected allylic alcohols with Pd catalysts according to a novel, designed catalytic cycle. Proposed intermediates in a "diverted Heck" mechanism are observed by means of spectroscopic studies and by isolation and X-ray crystallographic characterization, which together with reaction kinetics point to a separation of rate-determining and product-determining steps, and a mechanism-based optimization of the yield, selectivity, and scope of the catalytic electrophilic cyclopropanation. The reaction with crystalline, air-stable, nonhygroscopic, and nontoxic reagents provides an alternative to Simmons Smith-type reactions, as well as cyclopropanation procedures that require the use of diazomethane.
• BRANDT S.; HELQUIST P., J. AMER. CHEM. SOC., 1979, 101, NO 21, 6473-6475
  作者：BRANDT S.、 HELQUIST P.

  DOI：——

  日期：——
• (.eta.5-C5H5)(CO)2FeCH2S+(CH3)2 BF4-: a methylene transfer reagent for the direct cyclopropanation of alkenes
  作者：Edward J. O'Connor、Steven Brandt、Paul Helquist

  DOI：10.1021/ja00246a036

  日期：1987.6