3-[1-(4-bromophenyl)cyclopropyl]-8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine | 1403396-20-2

分子结构分类

有机化合物 - 苯类化合物 - 苯和取代衍生物

中文名称

——

中文别名

——

英文名称

3-[1-(4-bromophenyl)cyclopropyl]-8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine

英文别名

3-[1-(4-Bromophenyl)cyclopropyl]-8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine；[3-[1-(4-bromophenyl)cyclopropyl]-8-methyl-6,9-dihydro-5H-[1,2,4]triazolo[4,3-d][1,4]thiazepin-8-yl]methoxy-tert-butyl-dimethylsilane

3-[1-(4-bromophenyl)cyclopropyl]-8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine化学式

CAS

1403396-20-2

化学式

C₂₃H₃₄BrN₃OSSi

mdl

——

分子量

508.598

InChiKey

LHAOPLUCLBFRDZ-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

6.19
重原子数：

30
可旋转键数：

6
环数：

4.0
sp3杂化的碳原子比例：

0.65
拓扑面积：

65.2
氢给体数：

0
氢受体数：

4

上下游信息

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-[1-(4-pyrimidin-2-ylphenyl)cyclopropyl]-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-45-1	C₂₇H₃₇N₅OSSi	507.775
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(5-methylpyrimidin-2-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-60-0	C₂₈H₃₉N₅OSSi	521.802
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-[1-(4-pyrazin-2-ylphenyl)cyclopropyl]-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-47-3	C₂₇H₃₇N₅OSSi	507.775
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-[1-(4-pyridin-2-ylphenyl)cyclopropyl]-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-22-4	C₂₈H₃₈N₄OSSi	506.787
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-41-7	C₂₇H₃₉N₅OSSi	509.791
——	3-{1-[4-(5-bromopyridin-3-yl)phenyl]cyclopropyl}-8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-26-8	C₂₈H₃₇BrN₄OSSi	585.683
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-3-[1-(4-isoxazol-4-ylphenyl)cyclopropyl]-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-85-9	C₂₆H₃₆N₄O₂SSi	496.749
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(1H-pyrazol-5-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-92-8	C₂₆H₃₇N₅OSSi	495.764
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(6-methylpyridin-3-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-24-6	C₂₉H₄₀N₄OSSi	520.814
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(3-methyl-1H-pyrazol-4-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-87-1	C₂₇H₃₉N₅OSSi	509.791
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-[1-(4-pyridazin-3-ylphenyl)cyclopropyl]-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-59-7	C₂₇H₃₇N₅OSSi	507.775
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(4-methylpyridin-3-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-25-7	C₂₉H₄₀N₄OSSi	520.814
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(4-methylpyridin-2-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-30-4	C₂₉H₄₀N₄OSSi	520.814
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(2-methylpyridin-3-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-23-5	C₂₉H₄₀N₄OSSi	520.814
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-3-{1-[4-(5-chloropyridin-2-yl)phenyl]cyclopropyl}-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-64-4	C₂₈H₃₇ClN₄OSSi	541.232
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(1,3-oxazol-2-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-93-9	C₂₆H₃₆N₄O₂SSi	496.749
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(1,3-thiazol-2-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-48-4	C₂₆H₃₆N₄OS₂Si	512.816
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(5-methylpyridin-2-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-29-1	C₂₉H₄₀N₄OSSi	520.814
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(1-methyl-1H-imidazol-4-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-69-9	C₂₇H₃₉N₅OSSi	509.791
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-3-{1-[4-(5-fluoropyridin-2-yl)phenyl]cyclopropyl}-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-65-5	C₂₈H₃₇FN₄OSSi	524.778
——	5-(4-{1-[8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepin-3-yl]cyclopropyl}phenyl)pyridine-2-carbonitrile	1403396-54-2	C₂₉H₃₇N₅OSSi	531.797
——	5-(4-{1-[8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepin-3-yl]cyclopropyl}phenyl)nicotinonitrile	1403396-76-8	C₂₉H₃₇N₅OSSi	531.797
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-3-{1-[4-(1-ethyl-1H-pyrazol-4-yl)phenyl]cyclopropyl}-8-methyl-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-82-6	C₂₈H₄₁N₅OSSi	523.818
——	8-({[tert-butyl(dimethyl)silyl]oxy}methyl)-8-methyl-3-{1-[4-(6-methylpyridin-2-yl)phenyl]cyclopropyl}-5,6,8,9-tetrahydro[1,2,4]triazolo[4,3-d][1,4]thiazepine	1403396-28-0