3-(2-(4-((2-hydroxy-3H-indol-3-ylidene)amino)-5-(4-nitrophenyl)-4H-1,2,4-triazol-3-yl)hydrazineylidene)-3H-indol-2-ol | 1350294-03-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3-(2-(4-((2-hydroxy-3H-indol-3-ylidene)amino)-5-(4-nitrophenyl)-4H-1,2,4-triazol-3-yl)hydrazineylidene)-3H-indol-2-ol
• CAS: 1350294-03-9
• 化学式: C₂₄H₁₅N₉O₄
• 分子量: 493.441
• InChiKey: UKZIYKMRHFOVIC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.83
• 重原子数：
  37.0
• 可旋转键数：
  5.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  168.8
• 氢给体数：
  3.0
• 氢受体数：
  10.0

反应信息

• 作为反应物：
  描述：

  praseodymium(III) chloride 、 3-(2-(4-((2-hydroxy-3H-indol-3-ylidene)amino)-5-(4-nitrophenyl)-4H-1,2,4-triazol-3-yl)hydrazineylidene)-3H-indol-2-ol 在 盐酸 作用下， 以 乙醇 为溶剂， 反应 13.0h， 以63%的产率得到[Pr(IPNHT)Cl(H₂O)]
  参考文献：
  名称：

  Singh, Shweta; Tripathi, Priti; Pandey, Om P., Journal of the Indian Chemical Society, 2013, vol. 90, # 5, p. 565 - 570

  摘要：

  DOI：
• 作为产物：
  描述：

  、 靛红 在 盐酸 作用下， 以 乙醇 为溶剂， 生成 3-(2-(4-((2-hydroxy-3H-indol-3-ylidene)amino)-5-(4-nitrophenyl)-4H-1,2,4-triazol-3-yl)hydrazineylidene)-3H-indol-2-ol
  参考文献：
  名称：

  Singh, Shweta; Tripathi, Priti; Pandey, Om P., Journal of the Indian Chemical Society, 2013, vol. 90, # 5, p. 565 - 570

  摘要：

  DOI：

文献信息

• Synthesis, spectral characterization and biological activity of zinc(II) complexes with 3-substituted phenyl-4-amino-5-hydrazino-1, 2, 4-triazole Schiff bases
  作者：A.K. Singh、O.P. Pandey、S.K. Sengupta

  DOI：10.1016/j.saa.2011.08.019

  日期：2011.9

  New Zn(II) complexes have been synthesized by the reactions of zinc(II) acetate with Schiff bases derived from 3-substituted phenyl-4-amino-5-hydrazino-1, 2, 4-triazole and benzaldehyde, 2-hydroxyacetophenone or indoline-2,3-dione. All these complexes are soluble in DMF and DMSO; low molar conductance values indicate that they are non-electrolytes. Elemental analyses suggest that the complexes have 1:1 stoichiometry of the type [ZnL(H(2)O)(2)], [ZnL'(OAc)(2)(H(2)O)(2)] (L=dianionic Schiff bases derived from 3-(substituted phenyl)-4-amino-5-hydrazino-1, 2, 4-triazole and 2-hydroxyacetophenone or indoline-2,3-dione; L'=neutral Schiff bases derived from 3-(substituted phenyl)-4-amino-5-hydrazino-1, 2, 4-triazole and benzaldehyde) and they were characterized by FT-IR, (1)H NMR, (13)C NMR and FAB mass. All these Schiff bases and their complexes have also been screened for their antibacterial activities against Bacillus subtilis, Escherichia coli and antifungal activities against Colletotrichum falcatum, Aspergillus niger, Fusarium oxysporium and Carvularia pallescence by petriplates methods.
• Antioxidant, tautomerism and antibacterial studies of Fe(III)-1,2,4-triazole based complexes
  作者：G.J. Kharadi

  DOI：10.1016/j.saa.2013.03.068

  日期：2013.6

  New Fe(III) complexes have been synthesized by the reactions of ferric nitrate with Schiff base derived from 3-substituted phenyl-4-amino-5-hydrazino-1,2,4-triazole and indoline-2,3-dione. All these complexes are soluble in DMF and DMSO; low molar conductance values indicate that they are non-electrolytes. Elemental analyses suggest that the complexes have 1:1 stoichiometry of the type [FeLn(H2O)(OH)]center dot xH(2)O. Structural and spectroscopic properties have been studied on the basis of elemental analyses, infrared spectra, H-1 and H-13 NMR spectra, electronic spectra, magnetic measurements and FAB mass spectra. FT-IR, H-1 and H-13 NMR studies reveal that the ligand (L-n) exists in the tautomeric enol form in both the states with intramolecular hydrogen bonding. Magnetic moment and reflectance spectral studies reveal that an octahedral geometry has been assigned to all the prepared complexes. FRAP values indicate that all the compounds have a ferric reducing antioxidant power. The compounds 2 and 3 showed relatively high antioxidant activity while compound 1 and 4 shows poor antioxidant power. Also good antimicrobial activities of the complexes against Staphylococcus aureus, Bacillus subtilis, Serratia marcescens, Pseudomonas aeruginosa and Escherichia coli have been found compared to its free ligands. (C) 2013 Elsevier B.V. All rights reserved.