3,4-dihydro-2-morpholidethiazolidine-5-acetic morpholide | 104467-77-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: 3,4-dihydro-2-morpholidethiazolidine-5-acetic morpholide
• 英文别名: 2-Morpholin-4-yl-5-(2-morpholin-4-yl-2-oxoethyl)-1,3-thiazol-4-one
• CAS: 104467-77-8
• 化学式: C₁₃H₁₉N₃O₄S
• 分子量: 313.378
• InChiKey: CZWOIVYEOJCCDN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  96.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  在 吡啶 、 ammonium hydroxide 、 对甲苯磺酸 作用下， 以 苯 为溶剂， 反应 16.0h， 生成 3,4-dihydro-2-morpholidethiazolidine-5-acetic morpholide
  参考文献：
  名称：

  Zawisza, Tadeusz; Wagner, Edwin, Polish Journal of Chemistry, 1985, vol. 59, # 2, p. 149 - 158

  摘要：

  DOI：

文献信息

• New compounds
  申请人：Barf Tjeerd

  公开号：US20050239853A1

  公开（公告）日：2005-10-27

  The present invention relates to compounds with the formula (I) wherein R 1 , R 2 , R 3 , X, and Y are as defined herein, and also to pharmaceutical compositions comprising the compounds, as well as to the use of the compounds in medicine and for the preparation of a medicament which acts on the human 11-hydroxysteroid dehydrogenase type 1 enzyme.

  本发明涉及具有式（I）的化合物，其中R1，R2，R3，X和Y的定义如本文所述，以及包含该化合物的药物组合物，以及在医学上使用该化合物以及用于制备作用于人类11-羟基类固醇脱氢酶1型酶的药物的方法。
• Azole compounds, process for preparation of the same and use thereof
  申请人：Itoh Shigeyuki

  公开号：US20050009834A1

  公开（公告）日：2005-01-13

  The invention provides novel azole compounds useful as pest controllers and novel pest controllers containing the compounds as the active ingredient. The invention discloses azole compounds represented by the following general formula, a production process for preparation of the compounds, and use thereof as insecticides or acaricides: wherein X 1 to X 5 and Z 1 to Z 4 are each N, C—H, C-halogen, C-alkyl, or the like; Y 1 and Y 2 are each N or CH, with the proviso that both Y 1 and Y 2 must not be CH; A is a single bond, O, or the like; Ar is an optionally substituted aromatic residue; B is halogeno, alkyl, or the like; R 1 is H, halogeno, alkyl, or the like; R 2 and R 3 are each H, alkyl, or the like; m is 0 to 2; and n is 0 or 1.

  该发明提供了新型的唑类化合物，可用作害虫控制剂，以及含有该化合物作为活性成分的新型害虫控制剂。该发明揭示了由以下通式表示的唑类化合物，制备该化合物的生产工艺，并将其用作杀虫剂或螨虫剂：其中X1至X5和Z1至Z4均为N、C—H、C-卤素、C-烷基或类似物；Y1和Y2均为N或CH，但必须满足Y1和Y2不能同时为CH；A为单键、O或类似物；Ar为可选取代的芳香残基；B为卤素、烷基或类似物；R1为H、卤素、烷基或类似物；R2和R3均为H、烷基或类似物；m为0至2；n为0或1。
• AZOLE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF
  申请人：Sumitomo Chemical Takeda Agro Company, Limited

  公开号：EP1386915A1

  公开（公告）日：2004-02-04

  The invention provides novel azole compounds useful as pest controllers and novel pest controllers containing the compounds as the active ingredient. The invention discloses azole compounds represented by the following general formula, a production process for preparation of the compounds, and use thereof as insecticides or acaricides: wherein X1 to X5 and Z1 to Z4 are each N, C-H, C-halogen, C-alkyl, or the like; Y1 and Y2 are each N or CH, with the proviso that both Y1 and Y2 must not be CH; A is a single bond, O, or the like; Ar is an optionally substituted aromatic residue; B is halogeno, alkyl, or the like; R1 is H, halogeno, alkyl, or the like; R2 and R3 are each H, alkyl, or the like; m is 0 to 2; and n is 0 or 1.

  本发明提供了可用作害虫控制剂的新型唑类化合物，以及以该化合物为活性成分的新型害虫控制剂。本发明公开了由以下通式表示的唑类化合物、制备该化合物的生产工艺及其作为杀虫剂或杀螨剂的用途： 其中X1至X5和Z1至Z4各自为N、C-H、C-卤素、C-烷基或类似物；Y1和Y2各自为N或CH，但Y1和Y2均不得为CH；A为单键、O或类似物；Ar为任选取代的芳香残基；B为卤素、烷基或类似物；R1为H、卤素、烷基或类似物；R2和R3各自为H、烷基或类似物；m为0至2；n为0或1。
• ZAWISZA, T.;WAGNER, E., POL. J. CHEM., 1985, 59, N 2, 149-158
  作者：ZAWISZA, T.、WAGNER, E.

  DOI：——

  日期：——
• Zawisza, Tadeusz; Wagner, Edwin, Polish Journal of Chemistry, 1985, vol. 59, # 2, p. 149 - 158
  作者：Zawisza, Tadeusz、Wagner, Edwin

  DOI：——

  日期：——