2-硫代十二烷酸-1-甲酯钠 | 4016-21-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-硫代十二烷酸-1-甲酯钠
• 英文名称: Sodium Methyl-2-Sulfolaurate
• CAS: 4016-21-1
• 化学式: C13H26NaO5S
• 分子量: 317.4
• InChiKey: QJNQZLCZCZEFAW-UHFFFAOYSA-N

物化性质

• LogP：
  3.339 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  2.57
• 重原子数：
  20
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  89
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  、 N-乙烯基吡咯烷酮 、 2-硫代十二烷酸-1-甲酯钠 、 4-氯-3,5-二甲基苯酚 在 水 作用下， 以 水 为溶剂， 反应 368.0h， 生成 para-chloro-meta-xylenol
  参考文献：
  名称：

  Aqueous compositions containing a hydrophobic material

  摘要：

  一种含有疏水性物质的水性组合物，更具体地说，是由水溶性聚合物和水溶性表面活性剂构成的水溶性基质复合物，用于稳定疏水性物质，以纳米粒子分散或乳化形式存在。一种传递系统，用于传递生物活性疏水性物质，作为聚合物和表面活性剂的水溶性基质的水性纳米粒子分散液。

  公开号：

  US20100260691A1

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• [EN] ESTERAMINES AND DERIVATIVES FROM NATURAL OIL METATHESIS<br/>[FR] ESTERAMINES ET DÉRIVÉS DE MÉTATHÈSE D'HUILE NATURELLE
  申请人：STEPAN CO

  公开号：WO2012061093A1

  公开（公告）日：2012-05-10

  Esteramine compositions and their derivatives are disclosed. The esteramines comprise a reaction product of a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives with a tertiary alkanolamine. Derivatives made by quaternizing, sulfonating, alkoxylating, sulfating, and/or sulfitating the esteramines are also disclosed. In one aspect, the ester derivative of the C10-C17 monounsaturated acid or octadecene-1,18-dioic acid is a lower alkyl ester. In other aspects, the ester derivative is a modified triglyceride made by self-metathesis of a natural oil or an unsaturated triglyceride made by cross-metathesis of a natural oil with an olefin. The esteramines and derivatives are valuable for a wide variety of end uses, including cleaners, fabric treatment, hair conditioning, personal care (liquid cleansing products, conditioning bars, oral care products), antimicrobial compositions, agricultural uses, and oil field applications.

  本文公开了Esteramine组合物及其衍生物。Esteramine包括一种由交换反应得到的C10-C17单不饱和酸、十八烯-1,18-二羧酸或其酯衍生物与三级脂肪胺的反应产物。本文还公开了通过季铵化、磺化、烷氧基化、硫酸化和/或亚硫酸化Esteramine制备的衍生物。在一方面，C10-C17单不饱和酸或十八烯-1,18-二羧酸的酯衍生物是较低的烷基酯。在其他方面，酯衍生物是通过自交换天然油或通过天然油与烯烃的交叉交换得到的不饱和三酰甘油。Esteramine和衍生物对各种最终用途都有价值，包括清洁剂、织物处理、护发、个人护理（液体清洁产品、护理条、口腔护理产品）、抗菌组合物、农业用途和油田应用。
• SKIN CLEANSING COMPOSITIONS WITH POLYGLYCEROL ESTERS AND HYDROPHOBICALLY MODIFIED POLYMERS
  申请人：Anim-Danso Emmanuel

  公开号：US20120157366A1

  公开（公告）日：2012-06-21

  The methods and compositions of this invention relate to compositions containing polyglyceryl esters of fatty acids, low molecular weight hydrophobically-modified polymers and anionic and/or amphoteric surfactants having low irritation characteristics in combination with one or more additional characteristics, for example, relatively high clarity, relatively high foaming, and/or combinations thereof, as well as methods of making and using such compositions. These compositions have low pH values and are useful in cleansing the skin.

  本发明涉及一种含有脂肪酸聚甘油酯、低分子量疏水修饰聚合物和阴离子和/或两性表面活性剂的组合物的组成物和制备方法，具有低刺激性特征，同时具有相对高的清晰度、相对高的泡沫性能和/或其组合特性，以及使用这种组成物的方法。这些组成物具有低pH值，并且在清洁皮肤方面有用。
• UNSATURATED FATTY ALCOHOL DERIVATIVES FROM NATURAL OIL METATHESIS
  申请人：Stepan Company

  公开号：US20150087521A1

  公开（公告）日：2015-03-26

  Sulfate and sulfonate derivatives of unsaturated fatty alcohols, processes for making them, and methods of using them are disclosed. In one aspect, a monounsaturated fatty alcohol composition is made by reducing a metathesis-derived monounsaturated alkyl ester. The fatty alcohol composition is then converted to a sulfate or sulfonate derivative by one or more of alkoxylation, sulfation, sulfonation, and sulfitation. Of particular interest are the sulfate and ether sulfate derivatives.

  本发明涉及不饱和脂肪醇的硫酸盐和磺酸盐衍生物，其制备方法以及使用方法。在一方面，通过还原一种交换反应得到的单不饱和烷基酯来制备单不饱和脂肪醇组合物。然后，通过烷氧基化、硫酸化、磺化和亚硫酸化中的一种或多种方法将脂肪醇组合物转化为硫酸盐或磺酸盐衍生物。特别感兴趣的是硫酸盐和醚硫酸盐衍生物。