pentamethoxyisostegane | 87085-03-8

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物 - 木脂素内酯
• 英文名称: pentamethoxyisostegane
• 英文别名: (9R,13R)-3,4,5,17,18-pentamethoxy-11-oxatetracyclo[13.4.0.02,7.09,13]nonadeca-1(19),2,4,6,15,17-hexaen-10-one
• CAS: 87085-03-8；92693-31-7；117406-99-2；119069-44-2
• 化学式: C₂₃H₂₆O₇
• 分子量: 414.455
• InChiKey: YPKIMYGQCOKQPU-GOEBONIOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  72.4
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  pentamethoxyisostegane 生成 2-(1,3-benzodioxol-5-yl)-5-oxo-tetrahydrofuran-3-carboxylic acid
  参考文献：
  名称：

  CAMBIE, RICHARD C.;CRAW, PETER A.;RUTLEDGE, PETER S.;WOODGATE, PAUL D., AUSTRAL. J. CHEM., 41,(1988) N 6, C. 897-918

  摘要：

  DOI：
• 作为产物：
  描述：

  (-)-Thujaplicatin trimethyl ether 反应 3.0h， 以83%的产率得到pentamethoxyisostegane
  参考文献：
  名称：

  Synthesis of Dibenzocyclooctadienes by Anodic Oxidation

  摘要：

  Several lignoids with dibenzocyclooctadiene skeleton, such as schizandrins, domisins, schizantherins, stegans and kadsurins, have been reported to possess interesting biological activities (WAGNER, 1980: KUPCHAN, 1973) 1,2. Among them steganacin, isolated from Steganotaenia araliaceae Hochst., has been a synthetic target because of its antileukemic activity 2.

  DOI：

  10.1080/00397919108021280

文献信息

• CAMBIE, RICHARD C.;CRAW, PETER A.;RUTLEDGE, PETER S.;WOODGATE, PAUL D., AUSTRAL. J. CHEM., 41,(1988) N 6, C. 897-918
  作者：CAMBIE, RICHARD C.、CRAW, PETER A.、RUTLEDGE, PETER S.、WOODGATE, PAUL D.

  DOI：——

  日期：——
• Synthesis of Dibenzocyclooctadienes by Anodic Oxidation
  作者：João B. Fernandes、Regina L. Fraga、Milton D. Capelato、Paulo C. Vierira、Massayoshi Yoshida、Massuo J. Kato

  DOI：10.1080/00397919108021280

  日期：1991.6

  Several lignoids with dibenzocyclooctadiene skeleton, such as schizandrins, domisins, schizantherins, stegans and kadsurins, have been reported to possess interesting biological activities (WAGNER, 1980: KUPCHAN, 1973) 1,2. Among them steganacin, isolated from Steganotaenia araliaceae Hochst., has been a synthetic target because of its antileukemic activity 2.