甲基1,4-二甲基环己甲酸酯 | 23250-42-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 甲基1,4-二甲基环己甲酸酯
• 英文名称: Cyclohexanecarboxylic acid, 1,4-dimethyl-, methyl ester, trans-
• 英文别名: methyl 1,4-dimethylcyclohexane-1-carboxylate
• CAS: 23250-42-2；23059-38-3
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.25
• InChiKey: YLQLGTFGVSLQJL-UHFFFAOYSA-N

物化性质

• LogP：
  3.270 (est)
• 保留指数：
  1372.7;1398.5;1406.9

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] PHENYL-[4-(3-PHENYL-1H-PYRAZOL-4-YL)-PYRIMIDIN-2-Yl)-AMINE DERIVATIVES<br/>[FR] DERIVES DE PHENYL-[4-(3-PHENYL-1H-PYRAZOL-4-YL)-PYRIMIDIN-2-YL)-AMINE
  申请人：NOVARTIS AG

  公开号：WO2004005282A1

  公开（公告）日：2004-01-15

  The invention relates to phenyl-[4-(3-phenyl-1H-pyrazol-4-yl)-pyrimidin-2-yl)-amine derivatives and to processes for the preparation thereof, to pharmaceutical compositions comprising such derivatives and to the use of such derivatives - alone or in combination with one or more other pharmaceutically active compounds - for the preparation of pharmaceutical compositions for the treatment especially of a proliferative disease, such as a tumour.

  这项发明涉及苯基-[4-(3-苯基-1H-吡唑-4-基)-嘧啶-2-基)-胺衍生物，以及其制备方法，包括含有这种衍生物的药物组合物，以及使用这种衍生物 - 单独或与一个或多个其他药用活性化合物结合 - 制备用于治疗增生性疾病，如肿瘤的药物组合物。
• Dimethylcyclohexyl Derivatives as Malodor Neutralizers
  申请人：Flachsmann Felix

  公开号：US20100209378A1

  公开（公告）日：2010-08-19

  Compound of formula (I) wherein the dotted line is no bond or the dotted line together with the carbon-carbon bond represents a double bond; X and Y represent independently carbonyl, —CH 2 —, —CHMe-, or —C(Me) 2 -; and n and m are independently 0 or 1; with the proviso that if X is carbonyl either or both of n or m is 0, and their use as malodor counteractant. Furthermore, a process of their production and consumer products comprising them is described.

  化合物的公式（I），其中虚线代表没有键或虚线与碳-碳键一起表示双键；X和Y分别代表独立的羰基，—CH2—，—CHMe-，或—C（Me）2-；n和m独立地为0或1；条件是如果X是羰基，n或m中的一个或两个都是0；它们的用途是作为消除恶臭剂。此外，描述了它们的生产过程和包含它们的消费产品。
• Compositions comprising encapsulated material
  申请人：Ness Nicholas Jeremy

  公开号：US20060039934A1

  公开（公告）日：2006-02-23

  A composition such as a water-based consumer product comprises material (e.g. perfume) encapsulated within shell capsules, each capsule comprising an encapsulating wall having an inner surface and an outer surface, with a coating on the inner surface and/or outer surface of the shell wall, the composition further comprising surfactant and/or solvent. The coating can improve the barrier properties of the shell and can enhance retention of the encapsulated materials within the shell.

  一种水基消费品的组合物，包括封装在壳体胶囊内的材料（例如香水），每个胶囊包括具有内表面和外表面的封装壁，壳体壁的内表面和/或外表面上有涂层，组合物进一步包括表面活性剂和/或溶剂。涂层可以改善壳体的屏障性能，并可以增强封装材料在壳体内的保留能力。
• Alpha-Silyl Alcohols Possessing Olfactory Properties Reminiscent Of Patchouli Oil
  申请人：Kraft Philip

  公开号：US20120040879A1

  公开（公告）日：2012-02-16

  The present disclosure refers to sila-substituted carbinols of formula (I) wherein R 1 , R 2 and R 3 are independently selected from C 1 -C 4 alkyl or C 3 -C 4 cycloalkyl; R 4 is methyl or ethyl; and R 5 is methyl or ethyl. The disclosure further refers to their preparation and to perfume compositions and fragrance applications comprising them.

  本公开涉及式（I）的硅取代的碳醇，其中R1，R2和R3独立地选自C1-C4烷基或C3-C4环烷基; R4为甲基或乙基; R5为甲基或乙基。本公开进一步涉及它们的制备以及包括它们的香水组合物和香料应用。
• Fragranced compositions comprising encapsulated material
  申请人：QUEST INTERNATIONAL B.V.

  公开号：EP1393706A1

  公开（公告）日：2004-03-03

  A fragranced composition such as a water-based consumer product comprises material (e.g. perfume) encapsulated within shell capsules, each capsule comprising an encapsulating wall having an inner surface and an outer surface, with a coating on the inner surface and/or outer surface of the shell wall, the composition further comprising surfactant and/or solvent. The coating can improve the barrier properties of the shell and can enhance retention of the encapsulated materials within the shell.

  一种香味组合物，如水基消费品，包括封装在外壳胶囊中的材料（如香水），每个胶囊包括一个具有内表面和外表面的封装壁，外壳壁的内表面和/或外表面有一层涂层，组合物还包括表面活性剂和/或溶剂。涂层可以提高外壳的阻隔性能，并能增强封装材料在外壳内的保留。