2-Chloro4-hydroxyhexanoic acid | 238070-07-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羟基酸及其衍生物
• 英文名称: 2-Chloro4-hydroxyhexanoic acid
• 英文别名: 2-chloro-4-hydroxyhexanoic acid
• CAS: 238070-07-0
• 化学式: C₆H₁₁ClO₃
• 分子量: 166.6
• InChiKey: BRKNSOONGQHLKY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Use of alkanoic acid-containing compositions for straightening hair
  申请人：Buck, Carol J.

  公开号：EP1709960A2

  公开（公告）日：2006-10-11

  Compositions comprising at least one alkanoic acid in aqueous solution and use thereof for treating the keratin-related condition straightening hair.

  在水溶液中包含至少一种烷酸的组合物及其在治疗与角蛋白相关的直发状况时的用途。
• Formulations and methods for straightening hair
  申请人：——

  公开号：US20030143173A1

  公开（公告）日：2003-07-31

  Compositions and methods for treating keratin-related conditions and disorders such as straightening and styling hair, treating nail fungal conditions such as onychomycosis, ingrown nails, and hyperkeratotic conditions of the epidermis such as psoriasis, acne, callouses, corns, verruca, particularly plantar warts, and surface lines and blemishes of aging skin by aiding the exfoliation of keratinocytes. The compositions comprise at least one alkanoic acid in aqueous solution.

  用于治疗与角蛋白有关的病症和失调的组合物和方法，例如拉直和定型头发，治疗甲真菌病症，例如甲癣、嵌甲，以及表皮角化过度病症，例如牛皮癣、痤疮、胼胝、鸡眼、疣（尤其是跖疣），以及通过帮助角质细胞脱落老化皮肤的表面纹路和瑕疵。组合物包含至少一种烷酸水溶液。
• Synergistically pro-penetrating solutions for ungual/peri-ungual dermatological/cosmetic applications
  申请人：Ferrandis Agnes

  公开号：US20050181999A1

  公开（公告）日：2005-08-18

  Topically applicable dermatological/cosmetic compositions suited for ungual/peri-ungual administration for the treatment of a variety of pathologies, including fungal pathologies, such as onychomycosis, contain (a) at least one biologically active agent (e.g., antifungal) and (b) at least two of the pro-penetrating agents selected from the group consisting of urea, an organic acid and an ethoxydiglycol, the at least two-pro-penetrating agents respectively being present in effective amounts as to synergistically improve the ungual/peri-ungual bioavailability of the at least one biologically active agent.

  适用于单侧/经单侧给药的局部皮肤病学/化妆品组合物，用于治疗各种病症，包括真菌性病症，如癣菌病，含有(a)至少一种生物活性剂（如抗真菌剂）和(b)至少两种原渗透剂，这些原渗透剂选自由尿素、有机酸和乙氧基二甘醇组成的组、(b) 至少两种从尿素、有机酸和乙氧基二甘醇组成的组中选出的促渗透剂，至少两种促渗透剂分别以有效量存在，以协同提高至少一种生物活性剂在口腔/足周的生物利用率。
• COMPOSITIONS AND METHODS OF TREATING KERATIN-RELATED DISORDERS AND CONDITIONS
  申请人：Buck, Carol J.

  公开号：EP1052963A1

  公开（公告）日：2000-11-22
• EP1052963A4
  申请人：——

  公开号：EP1052963A4

  公开（公告）日：2003-08-06