2-羟基-7-甲基蒽-9,10-二酮 | 83312-51-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 中文名称: 2-羟基-7-甲基蒽-9,10-二酮
• 英文名称: 7-hydroxy-2-methylanthraquinone
• 英文别名: 7-hydroxytectoquinone；2-hydroxy-7-methylanthracene-9,10-dione
• CAS: 83312-51-0
• 化学式: C₁₅H₁₀O₃
• 分子量: 238.243
• InChiKey: UMJCTADKPMCLGQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-羟基-7-甲基蒽-9,10-二酮 、 碘甲烷 、 氧化银 生成 2-methoxy-7-methyl-9,10-anthraquinone
  参考文献：
  名称：

  KELLY, T. R.;PAREKH, N. D.;TRACHTENBERG, E. N., J. ORG. CHEM., 1982, 47, N 25, 5009-5013

  摘要：

  DOI：
• 作为产物：
  描述：

  反式-1-甲氧基-3-甲基-1,3-丁二烯 、 6-hydroxy-[1,4]naphthoquinone 以 丙酮 为溶剂， 生成 2-羟基-6-甲基蒽-9,10-二酮 、 2-羟基-7-甲基蒽-9,10-二酮
  参考文献：
  名称：

  Regiochemical control in the Diels-Alder reaction of substituted naphthoquinones. The directing effects of C-6 oxygen substitutents

  摘要：

  DOI：

  10.1021/jo00146a034

文献信息

• TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION
  申请人：ETH Zurich

  公开号：EP3801507A2

  公开（公告）日：2021-04-14
• ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS
  申请人：The Board of Regents of the University of Texas System

  公开号：US20160220510A1

  公开（公告）日：2016-08-04

  An aminoacylation/translation (AIT) system based on the protein synthesis system from the pathogen Pseudomonas aeruginosa , was used to screen chemical compounds for identifying inhibitors of protein synthesis. This system includes elongation factors: EF-Tu, EF-Ts and EF-G, aminoacyl tRNA synthetase (aaRS) specific for phenylalanine, PheRS, and ribosomes isolated from cultures of Pseudomonas aeruginosa . Compounds identified using this assay have been shown to contain broad spectrum activity against both Gram+ and Gram− pathogens. Methods of using the identified compounds, as well as derivatives and analogues of these compounds, as antimicrobial agents against bacterial infections are described.
• Regiochemical control in the Diels-Alder reaction of substituted naphthoquinones. The directing effects of C-6 oxygen substitutents
  作者：T. Ross Kelly、Nitin D. Parekh、Edward N. Trachtenberg

  DOI：10.1021/jo00146a034

  日期：1982.12
• KELLY, T. R.;PAREKH, N. D.;TRACHTENBERG, E. N., J. ORG. CHEM., 1982, 47, N 25, 5009-5013
  作者：KELLY, T. R.、PAREKH, N. D.、TRACHTENBERG, E. N.

  DOI：——

  日期：——