[2-amino-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone | 1228311-57-6

分子结构分类

有机化合物 - 有机杂环化合物 - 二氮杂萘

中文名称

——

中文别名

——

英文名称

[2-amino-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone

英文别名

[2-amino-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone

CAS

1228311-57-6

化学式

C₂₃H₂₅BN₄O₃

mdl

——

分子量

416.287

InChiKey

PNPDQAGURDTASD-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

2.67
重原子数：

31
可旋转键数：

2
环数：

5.0
sp3杂化的碳原子比例：

0.35
拓扑面积：

90.6
氢给体数：

1
氢受体数：

6

上下游信息

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	2-[2-amino-4-(isoindoline-2-carbonyl)quinazolin-6-yl]-5-hydroxybenzaldehyde	1367455-70-6	C₂₄H₁₈N₄O₃	410.432
——	(2-amino-6-{2-[(cyclopropylmethylamino)methyl]phenyl}quinazolin-4-yl)-(1,3-dihydroisoindol-2-yl)methanone	1367454-77-0	C₂₈H₂₇N₅O	449.555
——	2-[2-amino-4-(isoindoline-2-carbonyl)quinazolin-6-yl]-5-fluorobenzaldehyde	1367455-69-3	C₂₄H₁₇FN₄O₂	412.423
——	2-[2-amino-4-(isoindoline-2-carbonyl)quinazolin-6-yl]-4-fluorobenzaldehyde	1367455-68-2	C₂₄H₁₇FN₄O₂	412.423
——	{2-amino-6-[2-(tert-butylaminomethyl)-4-fluorophenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone	1367454-45-2	C₂₈H₂₈FN₅O	469.562
——	2-[2-amino-4-(isoindoline-2-carbonyl)quinazolin-6-yl]-5-(2-dimethylaminoethoxy)benzaldehyde	1367455-71-7	C₂₈H₂₇N₅O₃	481.554
——	[2-amino-6-(2-aminomethyl-4,5-difluorophenyl)quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone	1367454-80-5	C₂₄H₁₉F₂N₅O	431.445
——	[2-amino-6-[4-fluoro-2-(hydroxymethyl)phenyl]quinazolin-4-yl]isoindolin-2-ylmethanone	1367454-31-6	C₂₄H₁₉FN₄O₂	414.439
——	[2-amino-6-(2-chloromethyl-5-fluorophenyl)quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone	1367455-83-1	C₂₄H₁₈ClFN₄O	432.885
——	[2-amino-6-(2-{[ethyl-(2-hydroxyethyl)amino]methyl}-4-fluorophenyl)quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone	1367454-42-9	C₂₈H₂₈FN₅O₂	485.561
——	{2-amino-6-[4-fluoro-2-(4-methylpiperazin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone	1367454-69-0	C₂₉H₂₉FN₆O	496.587
——	(2-amino-6-{2-[(ethylmethylamino)methyl]-5-fluorophenyl}quinazolin-4-yl)-(1,3-dihydroisoindol-2-yl)methanone	1367454-37-2	C₂₇H₂₆FN₅O	455.535
——	{2-amino-6-[2-(tert-butylaminomethyl)-5-fluorophenyl]-quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone	1367454-46-3	C₂₈H₂₈FN₅O	469.562
——	[2-amino-6-[5-fluoro-2-(hydroxymethyl)phenyl]quinazolin-4-yl]isoindolin-2-ylmethanone	1367454-30-5	C₂₄H₁₉FN₄O₂	414.439
——	[2-amino-6-(2-diethylaminomethyl-5-fluorophenyl)quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone	1367454-83-8	C₂₈H₂₈FN₅O	469.562
——	[2-amino-6-(2-{[ethyl-(2-hydroxyethyl)amino]methyl}-5-fluorophenyl)quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone	1367454-41-8	C₂₈H₂₈FN₅O₂	485.561
——	{2-amino-6-[5-fluoro-2-(4-methylpiperazin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone	1367454-68-9	C₂₉H₂₉FN₆O	496.587
——	{2-amino-6-[2-(tert-butylaminomethyl)-4,5-difluorophenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone	1367454-72-5	C₂₈H₂₇F₂N₅O	487.552
——	[2-amino-6-(2-chloromethyl-4,5-difluorophenyl)quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone	1367455-82-0	C₂₄H₁₇ClF₂N₄O	450.875
——	{2-amino-6-[2-(methylethylaminomethyl)-4,5-difluorophenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone	1367454-70-3	C₂₇H₂₅F₂N₅O	473.525
——	[2-amino-6-[4,5-difluoro-2-(hydroxymethyl)phenyl]quinazolin-4-yl]isoindolin-2-ylmethanone	1367454-32-7	C₂₄H₁₈F₂N₄O₂	432.429
——	{2-amino-6-[2-(diethylaminomethyl)-4,5-difluorophenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone	1367454-71-4	C₂₈H₂₇F₂N₅O	487.552
——	{2-amino-6-[4-fluoro-2-(2-methylpyrrolidin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone	1367454-61-2	C₂₉H₂₈FN₅O	481.573
——	3-amino-N-{2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]-4,5-difluorobenzyl}propionamide	1367455-52-4	C₂₇H₂₄F₂N₆O₂	502.523
——	N-{2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]-4,5-difluorobenzyl}-3-dimethylaminopropionamide	1367454-82-7	C₂₉H₂₈F₂N₆O₂	530.577
——	{2-amino-6-[4,5-difluoro-2-(4-methylpiperazin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone	1367454-78-1	C₂₉H₂₈F₂N₆O	514.578
——	[2-amino-6-(4,5-difluoro-2-pyrrolidin-1-ylmethylphenyl)quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone	1367454-74-7	C₂₈H₂₅F₂N₅O	485.536
——	[2-amino-6-(2-aminoxymethyl-4,5-difluorophenyl)quinazolin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone	1367454-89-4	C₂₄H₁₉F₂N₅O₂	447.444
——	{2-amino-6-[5-fluoro-2-(4-hydroxypiperidin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone	1367454-84-9	C₂₉H₂₈FN₅O₂	497.572
——	{2-amino-6-[5-fluoro-2-(2-methylpyrrolidin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone	1367454-62-3	C₂₉H₂₈FN₅O	481.573