19-(4-Thiophen-2-ylphenyl)-2,5,8,11,14-pentaoxa-18,20-diazatricyclo[13.7.0.017,21]docosa-1(15),16,18,21-tetraene | 1334477-83-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 19-(4-Thiophen-2-ylphenyl)-2,5,8,11,14-pentaoxa-18,20-diazatricyclo[13.7.0.017,21]docosa-1(15),16,18,21-tetraene
• 英文别名: 19-(4-thiophen-2-ylphenyl)-2,5,8,11,14-pentaoxa-18,20-diazatricyclo[13.7.0.017,21]docosa-1(15),16,18,21-tetraene
• CAS: 1334477-83-6
• 化学式: C₂₅H₂₆N₂O₅S
• 分子量: 466.558
• InChiKey: YHFFGZVQOREOJY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  33
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  103
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  4-(2-噻吩基)苯甲醛 、 4-氨基-5-硝基苯并-15-冠-5 在 sodium dithionite 、 ammonium hydroxide 作用下， 以 水 、 二甲基亚砜 为溶剂， 反应 15.0h， 以64%的产率得到19-(4-Thiophen-2-ylphenyl)-2,5,8,11,14-pentaoxa-18,20-diazatricyclo[13.7.0.017,21]docosa-1(15),16,18,21-tetraene
  参考文献：
  名称：

  Imidazo-benzo-15-crown-5 ethers bearing arylthienyl and bithienyl moieties as novel fluorescent chemosensors for Pd2+ and Cu2+

  摘要：

  Novel fluorescent ionophores bearing imidazo-arylthienyl or imidazo-bithienyl pi-conjugated bridges functionalized with one or two fused benzo-15-crown-5 ethers as receptor units are reported. The sensing ability of the compounds in the presence of metallic cations (Li+, Na+, K+, Ca2+, Zn2+, Cu2+, Ni2+, Pd2+, and Hg2+) and fluoride ion was studied in MeCN/DMSO solutions by absorption and emission spectroscopy. The experimental results indicate that all compounds could act as selective fluorimetric sensors for Cu2+ and Pd2+ and also for the fluoride ion, in the case of the bis-substituted crown ether derivatives. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.06.106