2-(2,4-diaminophenyl)-ethanol | 14572-93-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2,4-diaminophenyl)-ethanol
• 英文别名: 1-(β-hydroxyethyl)-2,4-diaminobenzene；2-(2',4'-diaminophenyl) ethanol；2-(2,4-diamino-phenyl)-ethanol；2-(2,4-diaminophenyl)ethanol；β-(2,4-Diamino-phenyl)-aethanol；β-(2,4-Diaminophenyl)ethanol；4-(2-Hydroxyethyl)-m-phenylenediamine
• CAS: 14572-93-1
• 化学式: C₈H₁₂N₂O
• 分子量: 152.196
• InChiKey: VQUSUEWNKVODST-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  72.3
• 氢给体数：
  3
• 氢受体数：
  3

安全信息

• 海关编码：
  2922199090

反应信息

• 作为反应物：
  描述：

  吲哚啉-6-胺 、 2-(2,4-diaminophenyl)-ethanol 在 sodium hydroxide 、 磷酸 、 氢溴酸 作用下， 以 正己烷 、 二氯甲烷 为溶剂， 生成 1-methyl-2,3-dihydro-indol-6-ol 、 6-羟基吲哚啉
  参考文献：
  名称：

  Preparation of 6-hydroxyindolines and their use for preparation of novel

  摘要：

  一种合成6-羟基吲哚啉和由此产生的新荧光染料的新方法，这些染料是基于环限制吲哚啉的罗丹明类染料。这些染料具有吸收和发射光谱，使它们在某些染料激光应用中特别有用。

  公开号：

  US05256799A1
• 作为产物：
  描述：

  β-(2,4-dinitrophenyl)ethyl nitrate 在 镍 氢气 作用下， 18.0~25.0 ℃ 、3.04 MPa 条件下， 生成 2-(2,4-diaminophenyl)-ethanol
  参考文献：
  名称：

  通过（硝基苯基）烷醇硝基酯加氢合成（氨基苯基）烷醇

  摘要：

  氨基（二氨基）苯基链烷醇是某些技术材料（聚合物、离子交换树脂、染料）[2 -4] 和生物活性物质 [5] 合成的半成品。获得这些化合物的已知方法基于硝基（二硝基）苯基链烷醇 [4, 6 9]、硝基芳醛 [8]、硝基胺醇 [10]、硝基烯烃氧化物 [3, 11] 和氨基苯基羧酸的还原或催化氢化[12] 或其酯 [13]。在过去的几十年里，研究人员的注意力被吸引到使用容易获得的硝基（二硝基）苯基链烷醇硝基酯，它们经常在初始芳基链烷醇的亚硝化过程中形成。这些化合物在合成代表酸、醛、酮、烯烃、醇等类别的芳族硝基化合物中用作半产品。 然而，这些硝基酯的还原过程研究还不够充分。报道的一些研究包括 13-4-硝基苯乙基硝酸酯 [14] 的加氢和水合肼 [2] 将其还原为 13-4-氨基苯乙醇 [2, 14, 15]（在 [15] 中，还原剂类型和标明了反应条件和氨基醇的产率）。我们已经彻底研究了一些 2-硝基-、3-硝基

  DOI：

  10.1007/bf02465833

文献信息

• Compositions for oxidatively dyeing keratin fibers and methods for using such compositions
  申请人：Lim Mu'Ill

  公开号：US20070209123A1

  公开（公告）日：2007-09-13

  Compositions for dyeing keratin fibers comprise (a) at least one keratin dyeing compound selected from aromatic systems which comprise at least one boronic acid or boronic ester moiety and which are capable of forming upon oxidation a nucleophile or an electrophile, (b) at least one additional keratin dyeing compound selected from the group consisting of auxiliary developers and auxiliary couplers, and (c) a cosmetically suitable medium. Methods for oxidatively dyeing keratin fibers comprise the steps of applying such compositions in the presence of an oxidizing agent and rinsing the hair. A hair coloring product in kit form comprises a first separately packaged container comprising a composition as described above and a second separately packaged container comprising an oxidizing agent.

  用于染色的组合物包括：(a)至少一种选自含有至少一个硼酸或硼酸酯基团的芳香族系统的角蛋白染料化合物，这些化合物在氧化时能够形成亲核物或亲电子物；(b)至少一种额外的角蛋白染料化合物，选自辅助显色剂和辅助偶联剂的组合；(c)一种化妆品适用的介质。氧化染角蛋白纤维的方法包括在氧化剂存在下应用这样的组合物，并冲洗头发。一种套装形式的头发染色产品包括一个第一独立包装容器，其中包含上述描述的组合物，以及一个第二独立包装容器，其中包含氧化剂。
• Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
  申请人：Lim Mu'lll

  公开号：US20060156481A1

  公开（公告）日：2006-07-20

  Compositions for the oxidative dyeing of keratin fibers, comprising a medium suitable for dyeing and at least one N-oxides of six-membered rings with one or two nitrogen atoms keratin dyeing compound. A method for oxidative dyeing of keratin fibers, comprising applying such compositions in the presence of an oxidizing agent, for a period sufficient to develop the desired coloration.

  氧化染色角蛋白纤维的配方，包括适用于染色的介质和至少一种含有一个或两个氮原子的六元环N-氧化物的角蛋白染料化合物。一种氧化染色角蛋白纤维的方法，包括在氧化剂存在下施用这种配方，以足够时间发展所需的着色。
• Coupling compounds and hair dyeing compositions containing them
  申请人：DyStar Textilfarben GmbH & Co. Deutschland KG

  公开号：EP1847528A1

  公开（公告）日：2007-10-24

  The present invention refers to compounds of the formula (I) wherein R1 is (C1-C4)-alkyl, (C1-C4)-alkyl which is substituted by hydroxy, (C1-C4)-alkoxy, hydroxy-(C1-C4)-alkoxy, CN, -COOR5, -CON(R5)2 or -N(R5)2 or is phenyl; R2 is hydrogen, methyl or ethyl; R3 is (C1-C4)-alkylsulfonyl, (C1-C4)-alkylsulfonyl which is substituted by hydroxy, halogen, cyano, (C1-C4)-alkoxy or -N(R5)2 or is -SO2-CH=CH2, -SO2N(R5)2 or -PO(OR5)2; R4 is hydrogen, (C2-C4)-alkyl which is substituted by hydroxy, (C1-C4)-alkoxy or hydroxy-(C1-C4)-alkoxy; each of R5, independently is hydrogen, (C1-C4)-alkyl or hydroxy-(C2-C4)-alkyl; whereas R3 is not -NHSO2CH3 if R2 and R4 are both hydrogen and R1 is methyl, as well as hair dye compostions containing them.

  本发明涉及以下式(I)的化合物其中R1是(C1-C4)-烷基，被羟基取代的(C1-C4)-烷基，(C1-C4)-氧烷基，羟基-(C1-C4)-氧烷基，CN，-COOR5，-CON(R5)2或-N(R5)2或是苯基；R2是氢，甲基或乙基；R3是(C1-C4)-烷基磺酰基，被羟基，卤素，氰基，(C1-C4)-氧烷基或-N(R5)2取代的(C1-C4)-烷基磺酰基，或是-SO2-CH=CH2，-SO2N(R5)2或-PO(OR5)2；R4是氢，被羟基，(C1-C4)-氧烷基或羟基-(C1-C4)-氧烷基取代的(C2-C4)-烷基；R5中的每一个独立地是氢，(C1-C4)-烷基或羟基-(C2-C4)-烷基；其中如果R2和R4都是氢且R1是甲基，则R3不是-NHSO2CH3，以及含有它们的染发组合物。
• Coupling compounds and hair dyeing compositions containg them
  申请人：DyStar Textilfarben GmbH & Co. Deutschland KG

  公开号：EP1847526A1

  公开（公告）日：2007-10-24

  The present invention refers to Compound of the formula (I) wherein X is oxygen or sulphur; R1 is (C1-C4)-alkyl, (C1-C4)-alkyl which is substituted by hydroxy, (C1-C4)-alkoxy, hydroxy-(C1-C4)-alkoxy, CN, -COOR6, -CON(R6)2 or -N(R6)2 or is phenyl; R2 is hydrogen, methyl or ethyl; R3 is hydrogen, (C1-C4)-alkylsulfonyl, (C1-C4)-alkylsulfonyl which is substituted by hydroxy, halogen, cyano, (C1-C4)-alkoxy or -N(R6)2 or is -SO2-CH=CH2, -SO2N(R6)2 or -PO(OR6)2; or R3 is hydroxy-(C1-C4)-alkyl if R4 and R5 are not hydrogen ; R4 is hydrogen, (C1-C4)-alkyl, (C1-C4)-alkyl which is substituted by hydroxy, (C1-C4)-alkoxy, or hydroxy-(C1-C4)-alkoxy ; R5 is hydrogen, (C1-C4)-alkyl, (C1-C4)-alkyl which is substituted by hydroxy, (C1-C4)-alkoxy or hydroxy-(C1-C4)-alkoxy ; R6 is hydrogen, (C1-C4)-alkyl or hydroxy-(C1-C4)-alkyl; whereas R3, R4 and R6 are all hydrogen or are different and whereas the compound of the formula (I) wherein R1 is methyl and R2 to R5 are hydrogen is diesclaimt, as well as hair dye compositions containing them.

  本发明涉及式(I)化合物，其中X为氧或硫；R1为(C1-C4)烷基、被羟基取代的(C1-C4)烷基、(C1-C4)烷氧基、羟基-(C1-C4)烷氧基、氰基、-COOR6、-CON(R6)2或-N(R6)2或为苯基；R2为氢、甲基或乙基；R3为氢、(C1-C4)烷基磺酰基、被羟基、卤素、氰基、(C1-C4)烷氧基或-N(R6)2取代的(C1-C4)烷基磺酰基，或为-SO2-CH=CH2、-SO2N(R6)2或-PO(OR6)2；或者，当R4和R5不为氢时，R3为羟基-(C1-C4)烷基；R4为氢、(C1-C4)烷基、被羟基、(C1-C4)烷氧基或羟基-(C1-C4)烷氧基取代的(C1-C4)烷基；R5为氢、(C1-C4)烷基、被羟基、(C1-C4)烷氧基或羟基-(C1-C4)烷氧基取代的(C1-C4)烷基；R6为氢、(C1-C4)烷基或羟基-(C1-C4)烷基；其中R3、R4和R6均为氢或不同，并且式(I)化合物中R1为甲基且R2至R5均为氢的化合物除外，以及含有它们的染发组合物。
• Novel hair coloring compositions for use in oxidative hair dyeing
  申请人：Lim Mu'lll

  公开号：US20050188480A1

  公开（公告）日：2005-09-01

  Hair dyeing compositions are provided which comprise at least one coupler selected from N-aryl-m-phenylenediamine derivatives, 2-substituted N-aryl-m-phenylenediamine derivatives, and N-aryl-m-diaminopyridine derivatives, in combination with and at least one diaminopyrazole primary intermediate.

  提供了包括至少一种偶联剂在内的染发配方，所选偶联剂包括N-芳基-m-苯二胺衍生物、2-取代N-芳基-m-苯二胺衍生物和N-芳基-m-二氨基吡啶衍生物，与至少一种二氨基吡唑原料中间体组合使用。