3-indoleacetylsalicylic acid | 84289-36-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 3-indoleacetylsalicylic acid
• 英文别名: 2-[2-(1H-indol-3-yl)acetyl]oxybenzoic acid
• CAS: 84289-36-1
• 化学式: C₁₇H₁₃NO₄
• 分子量: 295.295
• InChiKey: YSQMCYBVNVVOIM-UHFFFAOYSA-N

物化性质

• 熔点：
  127 °C
• 沸点：
  570.0±40.0 °C(Predicted)
• 密度：
  1.388±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  79.4
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  吲哚乙酰氯 、 水杨酸 在 N-乙基哌啶 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 以44%的产率得到3-indoleacetylsalicylic acid
  参考文献：
  名称：

  El-Gendy; Osman; Khalifa, Pharmazie, 1982, vol. 37, # 7, p. 481 - 482

  摘要：

  DOI：

文献信息

• EL-GENDY, A. A.;OSMAN, A. N.;KHALIFA, M., PHARMAZIE, 1982, 37, N 7, 481-482
  作者：EL-GENDY, A. A.、OSMAN, A. N.、KHALIFA, M.

  DOI：——

  日期：——
• METHOD FOR PROFILING PHYTOHORMONE LEVELS IN PLANT TISSUE
  申请人：BASF Plant Science Company GmbH

  公开号：EP2697640A1

  公开（公告）日：2014-02-19
• [EN] METHOD FOR PROFILING PHYTOHORMONE LEVELS IN PLANT TISSUE<br/>[FR] PROCÉDÉ POUR L'ÉTABLISSEMENT DU PROFIL DE NIVEAUX DE PHYTOHORMONES DANS UN TISSU VÉGÉTAL
  申请人：BASF PLANT SCIENCE CO GMBH

  公开号：WO2012140603A1

  公开（公告）日：2012-10-18

  The present invention provides a method for profiling phytohormone levels in plant tissue or tissue of other plastid containing organisms, i.e. a method for the simultaneous determination of a multitude of phytohormone levels in plant tissue or tissue of other plastid containing organisms, which method comprises the following steps: i. extraction of particulate tissue material of the plastid containing organism, in particulate tissue material of plants, with a liquid extractant, which is a mixture of at least one water miscible neutral organic solvent having from 1 to 3 carbon atoms and 1 heteroatom selected from O and N with water containing from 0.1 to 5% by weight, based on the extractant, of at least one acid, whereby a first liquid extract is obtained; ii. contacting the liquid extract obtained in step i. with a solid absorbent having a hydrophobically modified surface and removing the solid absorbent to obtain a second liquid extract; iii. evaporating the solvent from the second extract and then re-dissolving the obtained residue in a solvent mixture of at least one water miscible neutral organic solvent having from 1 to 3 carbon atoms and 1 heteroatom selected from O and N with water containing from 0.1 to 5% by weight, based on the solvent mixture, of at least one acid to obtain a reconstituted extract; iv. purification of the reconstituted extract by contacting it with a solid absorbent having a hydrophobically modified surface to obtain a purified reconstituted extract (eluate); and v. determining the relative concentrations of at least two, frequently at least 4, in particular at least 6, especially at least 8 or at least 10 phyto, e.g. from 2 to 60, frequently from 4 to 50, in particular from 6 to 45, especially from 8 to 40 or from 10 to 30 plant hormones (phytohormones) in the purified reconstituted extract obtained in step iv. by directly subjecting the purified reconstituted extract to an analyzing unit comprising a separation unit for separation the phytohormones and an analyzer for identifying the phytohormones which separation unit is coupled to the analyzer.
• El-Gendy; Osman; Khalifa, Pharmazie, 1982, vol. 37, # 7, p. 481 - 482
  作者：El-Gendy、Osman、Khalifa

  DOI：——

  日期：——