p-chlorophenyloxalythiosemicarbazide | 33327-11-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: p-chlorophenyloxalythiosemicarbazide
• 英文别名: 4,4'-Di-p-chlorphenyl-oxalylthiosemicarbazid；1,1-oxalyl-bis(4-p-chlorophenylthiosemicarbazide)；1-(4-Chlorophenyl)-3-[[2-[2-[(4-chlorophenyl)carbamothioyl]hydrazinyl]-2-oxoacetyl]amino]thiourea
• CAS: 33327-11-6
• 化学式: C₁₆H₁₄Cl₂N₆O₂S₂
• 分子量: 457.364
• InChiKey: LWICNUJHGJNCJK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  28
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  171
• 氢给体数：
  6
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  p-chlorophenyloxalythiosemicarbazide 以60%的产率得到
  参考文献：
  名称：

  KUDARI, S. M.;SANGAPURE, S. S., CURR. SCI., INDIA, 1984, 53, N 20, 1086-1088

  摘要：

  DOI：
• 作为产物：
  描述：

  乙二酸二酰肼 、 4-氯异硫氰酸苯酯 以81%的产率得到
  参考文献：
  名称：

  KUDARI, S. M.;SANGAPURE, S. S., CURR. SCI., INDIA, 1984, 53, N 20, 1086-1088

  摘要：

  DOI：

文献信息

• RAM V. J.; PANDEY H. N., BULL. SOC. CHIM. BELG. <BSCB-AG>, 1977, 86 NO 5, 399-403
  作者：RAM V. J.、 PANDEY H. N.

  DOI：——

  日期：——
• Spectroscopic, thermogravimetric and antibacterial studies for some bivalent metal complexes of oxalyl-, malonyl- and succinyl-bis(4-p-chlorophenylthiosemicarbazide)
  作者：Ragab R. Amin、Yamany B. Yamany

  DOI：10.1016/j.molstruc.2011.11.024

  日期：2012.1

  Anodic oxidation of Co, Cu, Zn, and Sn metals in an anhydrous acetone solution of 1,1-oxaly1-, malonyl- or succinyl-bis(4-p-chlorophenylthiosemicarbazide) yields a new polynuclear complexes. The isolated complexes have the general composition [M-2(L)(H2O)(6)], L = pCISuTS and M = Co(II), Cu(II) or Sn(II), [M-2(L)(H2O)(n)]center dot nH(2)O where M = Cu(II), Co(II) or Sn(II), L = pCIOxTS and n = 2 or 6, and [M-2(L)(ac)(2)]center dot nH(2)O where M = Co(II) or Zn(II), L = pCIOxTS or pCISuTS and n = 2. The thermogravimetry (TG) and derivative thermogravimetry (DTG) have been used to study the thermal decomposition of the investigated bisthiosemicarbazide ligands and their metal complexes. The kinetic thermodynamic parameters such as: E., Delta H*, Delta S* and Delta G* are calculated using Horowitz-Metzger (HM) and Coats-Redfern (CR) equations. The kinetic thermodynamic parameters such as: E*, Delta H*, Delta S* and Delta G* are calculated from the DTG curves. The tested compounds show a reasonable activity against four strains of Gram-negative bacteria; Escherichia coli, Pseudomonas aeruginosa species and Gram-positive bacteria: Bacillus cereus and Staphylococcus aureus. (C) 2011 Elsevier B.V. All rights reserved.
• KUDARI, S. M.;SANGAPURE, S. S., CURR. SCI., INDIA, 1984, 53, N 20, 1086-1088
  作者：KUDARI, S. M.、SANGAPURE, S. S.

  DOI：——

  日期：——