α-benzoylamino-3-methyl-cinnamic acid | 72615-63-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: α-benzoylamino-3-methyl-cinnamic acid
• 英文别名: α-Benzimino-β-m-tolyl-propionsaeure；α-Benzamino-β-m-tolyl-acrylsaeure；α-Benzimino-3-methyl-hydrozimtsaeure；α-Oxo-β-m-tolyl-propionsaeure；α-Benzoylamino-3-methyl-zimtsaeure；α-Benzamino-3-methyl-zimtsaeure；(E)-2-benzamido-3-(3-methylphenyl)prop-2-enoic acid
• CAS: 72615-63-5
• 化学式: C₁₇H₁₅NO₃
• 分子量: 281.311
• InChiKey: PFCZGQSNQUOWII-RVDMUPIBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  α-benzoylamino-3-methyl-cinnamic acid 在 盐酸 、 sodium amalgam 、 水 作用下， 生成 DL-3-甲基苯丙氨酸
  参考文献：
  名称：

  Low back pain patients in primary care: Subgroups based on the multidimensional pain inventory

  摘要：

  Classification of patients into homogeneous subgroups is an important objective in primary care management of low back pain patients. The purpose of this study is to (a) identify and describe cluster profiles based on self-reported multidimensional pain inventory Scale (MPI) scores among subacute and chronic nonspecific low back pain patients; Cb) describe characteristics of the clusters in relation to disability, life satisfaction, functional self-efficacy, and exercise self-efficacy; and (c) compare grouping by clusters based on self-reported MPI scores with grouping by symptom duration. Eighty-eight individuals participated. These had a median lower back pain duration of 7 months (range 1 to 144 months). Three clusters were identified; these were labeled interpersonally distressed, adaptive copers, and dysfunctional. The clusters differed significantly in disability and functional self-efficacy scores, but not in life satisfaction and exercise self-efficacy scores. The results of this study in a primary care setting are discussed in relation to previous results in pain clinic settings.

  DOI：

  10.1207/s15327558ijbm0704_05
• 作为产物：
  描述：

  马尿酸 、 3-甲基苯甲醛 在 sodium acetate 、 乙酸酐 作用下， 生成 α-benzoylamino-3-methyl-cinnamic acid
  参考文献：
  名称：

  Low back pain patients in primary care: Subgroups based on the multidimensional pain inventory

  摘要：

  Classification of patients into homogeneous subgroups is an important objective in primary care management of low back pain patients. The purpose of this study is to (a) identify and describe cluster profiles based on self-reported multidimensional pain inventory Scale (MPI) scores among subacute and chronic nonspecific low back pain patients; Cb) describe characteristics of the clusters in relation to disability, life satisfaction, functional self-efficacy, and exercise self-efficacy; and (c) compare grouping by clusters based on self-reported MPI scores with grouping by symptom duration. Eighty-eight individuals participated. These had a median lower back pain duration of 7 months (range 1 to 144 months). Three clusters were identified; these were labeled interpersonally distressed, adaptive copers, and dysfunctional. The clusters differed significantly in disability and functional self-efficacy scores, but not in life satisfaction and exercise self-efficacy scores. The results of this study in a primary care setting are discussed in relation to previous results in pain clinic settings.

  DOI：

  10.1207/s15327558ijbm0704_05

文献信息

• NICHOLAS E. S.; PHEIPS D. J., J. CHEM. AND ENG. DATA, 1980, 25, NO 1, 89-90
  作者：NICHOLAS E. S.、 PHEIPS D. J.

  DOI：——

  日期：——
• Low back pain patients in primary care: Subgroups based on the multidimensional pain inventory
  作者：Eva Johansson、Per Lindberg

  DOI：10.1207/s15327558ijbm0704_05

  日期：2000.12

  Classification of patients into homogeneous subgroups is an important objective in primary care management of low back pain patients. The purpose of this study is to (a) identify and describe cluster profiles based on self-reported multidimensional pain inventory Scale (MPI) scores among subacute and chronic nonspecific low back pain patients; Cb) describe characteristics of the clusters in relation to disability, life satisfaction, functional self-efficacy, and exercise self-efficacy; and (c) compare grouping by clusters based on self-reported MPI scores with grouping by symptom duration. Eighty-eight individuals participated. These had a median lower back pain duration of 7 months (range 1 to 144 months). Three clusters were identified; these were labeled interpersonally distressed, adaptive copers, and dysfunctional. The clusters differed significantly in disability and functional self-efficacy scores, but not in life satisfaction and exercise self-efficacy scores. The results of this study in a primary care setting are discussed in relation to previous results in pain clinic settings.