3,6,9,12-四氧杂十三烷-1-基甲基丙烯酸酯 | 57454-26-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 3,6,9,12-四氧杂十三烷-1-基甲基丙烯酸酯
• 英文名称: methoxytetraethyleneglycol methacrylate
• 英文别名: 2,5,8,11-tetraoxatridecan-13-yl methacrylate；MeO₄MA；3,6,9,12-Tetraoxatridec-1-yl methacrylate；2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl 2-methylprop-2-enoate
• CAS: 57454-26-9
• 化学式: C₁₃H₂₄O₆
• 分子量: 276.33
• InChiKey: KRCGBOKYIUDIFY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  19
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  63.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  甲基丙烯酸羟乙酯 、 甲基丙烯酰氯 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 3.17h， 以54%的产率得到3,6,9,12-四氧杂十三烷-1-基甲基丙烯酸酯
  参考文献：
  名称：

  Preparation of polymer latex particles carrying salt-responsive fluorescent graft chains

  摘要：

  We prepared the novel fluorescent polymer latex particles which can change their fluorescence intensity in response to the increasing NaCl concentration in water. Core polymer latex particles were synthesized by emulsifier-free emulsion polymerization of styrene and 2-(2-chloroisobutyroyloxy)ethyl methacrylate. Hydrophilic polymer chains containing epoxy groups were grafted from the core particles by surface-initiated atom transfer radical copolymerization of methoxy polyethyleneglycol methacrylate (MEO(x)MA, x = 4 or 9) and glycidyl methacrylate in aqueous media. After azidation of epoxy groups in graft chains, a water-soluble fluorescent dansyl derivative was successfully coupled with the graft chains by copper-catalyzed azide-alkyne cycloaddition in aqueous media. The wavelength of maximum fluorescence intensity of polymer particles carrying graft chains with longer PEG side chains (x = 9) was slightly blue-shifted (7 nm) and the fluorescence intensity increased (1.35 times) with an increase in NaCl concentration as opposed to polymer particles with shorter PEG chains (x = 4). (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.polymer.2014.08.030

文献信息

• CATALYST FOR LIVING RADICAL POLYMERIZATION
  申请人：Goto Atsushi

  公开号：US20110275775A1

  公开（公告）日：2011-11-10

  Provided is a catalyst used for a living radical polymerization method, which contains a central element consisting of carbon and at least one halogen atom binding to the central element. Further, a hydrocarbon compound can be used as a catalyst precursor. A monomer having a radical-reactive unsaturated bond is subjected to a radical polymerization reaction in the presence of the catalyst, consequently a polymer having narrow molecular weight distribution can be obtained, and thus the cost of the living radical polymerization can be remarkably reduced. The present invention is significantly more environmentally friendly and economically excellent than conventional living radical polymerization methods, due to advantages such as low toxicity of the catalyst, low amount of the catalyst used, high solubility of the catalyst, mild reaction conditions, and no coloration/no odor (no need of any post-treatments for a molded article), and the like.

  提供的是用于活性自由基聚合方法的催化剂，其包含由碳组成的中心元素，并且至少有一个卤素原子与中心元素结合。此外，碳氢化合物可以用作催化剂前体。在催化剂存在的情况下，将具有自由基反应不饱和键的单体进行自由基聚合反应，因此可以获得具有窄分子量分布的聚合物，从而可以显着降低活性自由基聚合的成本。由于催化剂毒性低、使用量少、催化剂溶解性高、反应条件温和、成品无色无味（无需对成型物进行任何后处理）等优点，本发明比传统的活性自由基聚合方法在环保和经济方面更加优越。
• Chemoselective Transesterification of Acrylate Derivatives for Functionalized Monomer Synthesis Using a Hard Zinc Alkoxide Generation Strategy
  作者：Daiki Nakatake、Ryo Yazaki、Takashi Ohshima

  DOI：10.1002/ejoc.201600737

  日期：2016.8

  functionalized acrylate derivatives with the view to prepare functional polymers was explored. Hard zinc alkoxide generation enabled the highly chemoselective transesterification of acrylate derivatives over the undesired conjugate addition, which caused polymerization. The combined use of the catalytic zinc cluster Zn4(OCOCF3)6O and 4-(dimethylamino)pyridine delivered various functionalized acrylate derivatives

  为了制备功能性聚合物，探索了一种合成功能化丙烯酸酯衍生物的实用新方法。硬锌醇盐生成使丙烯酸酯衍生物的高度化学选择性酯交换超过不希望的共轭加成，这会导致聚合。催化锌簇 Zn4(OCOCF3)6O 和 4-(二甲氨基)吡啶的联合使用通过在温和条件下将市售的丙烯酸甲酯衍生物与官能化醇进行酯交换，提供了各种官能化丙烯酸酯衍生物。
• Living radical polymerization initiator, method for producing polymer, and polymer
  申请人：KYOTO UNIVERSITY

  公开号：US10414848B2

  公开（公告）日：2019-09-17

  A living radical polymerization initiator represented by the following: wherein, R1 represents an aromatic, an alkylcarbonyl, an alkoxycarbonyl, an aminocarbonyl, an alkylaminocarbonyl, a dialkylaminocarbonyl, an arylcarbonyl, an alkylsulfonyl, an aryl sulfonyl or combinations thereof; R2, R3, R4 and R5 are a hydrogen, an aliphatic, an aromatic, an alkylcarbonyl, an alkoxycarbonyl, an aminocarbonyl, an alkylaminocarbonyl, a dialkylaminocarbonyl, an arylcarbonyl, a carboxy, an alkylsulfonyl or an aryl sulfonyl; X and Y are a halogen; m and n are an integer of 1 or more, and are non-symmetrical so that X and Y have different reactivities to initiate a living radical polymerization.

  一种由以下表示的活性自由基聚合引发剂：其中，R1代表芳香族、烷基羰基、烷氧羰基、氨基羰基、烷基氨基羰基、二烷基氨基羰基、芳基羰基、烷基磺酰基、芳基磺酰基或它们的组合；R2、R3、R4和R5分别为氢、脂肪族、芳香族、烷基羰基、烷氧羰基、氨基羰基、烷基氨基羰基、二烷基氨基羰基、芳基羰基、羧基、烷基磺酰基或芳基磺酰基；X和Y分别为卤素；m和n为1或更多的整数，并且非对称，以使X和Y具有不同的活性，以启动活性自由基聚合。
• Method for selectively removing virus and leukocytes eliminating material and eliminating apparatus
  申请人：Onodera Hirokazu

  公开号：US20050014127A1

  公开（公告）日：2005-01-20

  It is intended to provide a method whereby a virus and leukocytes can be simultaneously eliminated from virus-containing blood and platelets can be recovered at a high yield, and a material and an apparatus therefor. A water-soluble carrier having surface which is capable of capturing a virus and leukocytes in blood but allows the permeation of platelets therethrough is brought into contact with virus-containing blood. Thus the virus and leukocytes can be simultaneously removed from the blood while platelets can be recovered at a high yield.

  本发明旨在提供一种方法，可以同时从含病毒的血液中消除病毒和白细胞，并且可以高产地回收血小板，以及相应的材料和装置。将具有能够捕获血液中病毒和白细胞的表面但允许血小板透过的水溶性载体与含病毒的血液接触。因此，可以同时从血液中去除病毒和白细胞，同时可以高产地回收血小板。
• PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION
  申请人：Takagi Masatoshi

  公开号：US20100024683A1

  公开（公告）日：2010-02-04

  The invention provides a phosphate compound having an unsaturated double bond and a metal salt thereof; a dental material containing a phosphate compound having an unsaturated double bond and/or a metal salt thereof; and a dental composition containing a phosphate compound having an unsaturated double bond and/or a metal salt thereof. The phosphate compound of the invention provides a dental material and a dental composition such as a bonding material, adhesive material and a dental luting agent that are highly stable during storage, convenient for handling, and that exhibit higher adhesiveness and bond durability.

  本发明提供了一种具有不饱和双键的磷酸盐化合物及其金属盐；含有具有不饱和双键的磷酸盐化合物和/或其金属盐的牙科材料；以及含有具有不饱和双键的磷酸盐化合物和/或其金属盐的牙科组合物。本发明的磷酸盐化合物提供了一种牙科材料和牙科组合物，例如粘接材料、粘合剂和牙科粘接剂，在储存期间高度稳定，方便处理，并表现出更高的粘附性和粘接耐久性。