bis(3-bromo-4,5-dihydroxyphenyl)methanone | 1251090-67-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis(3-bromo-4,5-dihydroxyphenyl)methanone
• CAS: 1251090-67-1
• 化学式: C₁₃H₈Br₂O₅
• 分子量: 404.012
• InChiKey: QWGGKBRLOGNRAY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  98
• 氢给体数：
  4
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  bis(3-bromo-4,5-dihydroxyphenyl)methanone 在 四(三苯基膦)钯 、 potassium tert-butylate 、 potassium carbonate 作用下， 以 四氢呋喃 、 N-甲基吡咯烷酮 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 10.0h， 生成
  参考文献：
  名称：

  헤테로고리 화합물 및 이를 포함하는 유기 발광 소자

  摘要：

  这个规范书涉及到化学式1的杂环化合物和包含它的有机发光元件。

  公开号：

  KR20200032658A
• 作为产物：
  描述：

  双(3,4-二羟基苯基)甲酮 在 溴 、 溶剂黄146 作用下， 以50%的产率得到bis(3-bromo-4,5-dihydroxyphenyl)methanone
  参考文献：
  名称：

  Bromophenols as Candida albicans isocitrate lyase inhibitors

  摘要：

  A new series of bromophenols was synthesized by reactions of corresponding phenol analogs with bromine. The synthesized compounds were tested for inhibitory activity against isocitrate lyase (ICL) of Candida albicans and antimicrobial activity against Gram-positive and, Gram-negative bacteria and fungi. Among the synthesized bromophenols, bis(3-bromo-4,5-dihydroxyphenyl)methanone (11) and (3-bromo-4,5-dihydroxyphenyl)(2,3-dibromo-4,5-dihydroxyphenyl)methanone (12) displayed potent inhibitory activities against ICL, showing a stronger inhibitory effects than were found with natural bromophenol 1. The preliminary structure-activity relationships were investigated in order to determine the essential structural requirements for the inhibitory activities of these compounds against ICL of C. albicans. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.09.015

文献信息

• METHOD FOR PREPARING POLYMER AND POLYMER PREPARED THEREBY
  申请人：LG Chem, Ltd.

  公开号：EP2857425A1

  公开（公告）日：2015-04-08

  Provided is a method for preparing polymer. By additionally inputting a catalyst reducing agent that reduces an inactivated metal complex compound catalyst to an activated metal complex compound catalyst, a polymer polymerized at a high conversion ratio of a monomer can be provided.

  本发明提供了一种制备聚合物的方法。通过额外输入一种催化剂还原剂，将失活的金属络合物催化剂还原成活化的金属络合物催化剂，可以提供一种以高单体转化率聚合的聚合物。
• MULTI-BLOCK COPOLYMER
  申请人：LG Chem, Ltd.

  公开号：EP2993194A1

  公开（公告）日：2016-03-09

  Provided are a multi-block copolymer, a pressure-sensitive adhesive composition, a method of preparing a multi-block copolymer, a pressure-sensitive adhesive polarizing plate, and a liquid crystal display device. The pressure-sensitive adhesive composition including the multi-block copolymer may have excellent durability regardless of a temperature and/or humidity. In addition, the method of preparing a multi-block copolymer may prepare a multi-block copolymer increased in molecular weight which is structurally controlled with a simple process using a compound containing at least two halogen atoms. Accordingly, when included in a pressure-sensitive adhesive resin, the multi-block copolymer may have excellent cohesive strength in the resin, and a network structure during curing, and thus, when applied to a pressure-sensitive adhesive composition, the multi-block copolymer may be usefully applied to an optical member due to excellent durability regardless of a temperature and humidity.

  本文提供了一种多嵌段共聚物、一种压敏胶组合物、一种制备多嵌段共聚物的方法、一种压敏胶偏光板和一种液晶显示设备。包括多嵌段共聚物在内的压敏胶组合物不受温度和/或湿度的影响，可具有极佳的耐久性。此外，多嵌段共聚物的制备方法可制备出分子量增大的多嵌段共聚物，该共聚物可通过使用至少含有两个卤素原子的化合物的简单工艺进行结构控制。因此，当将多嵌段共聚物加入压敏型粘合剂树脂中时，该共聚物在树脂中可能具有优异的内聚强度，并在固化过程中具有网络结构，因此，当应用于压敏型粘合剂组合物时，该多嵌段共聚物由于具有优异的耐久性，无论温度和湿度如何，都可以有效地应用于光学部件。
• POLYMER PREPARING METHOD AND POLYMER PREPARED BY THE SAME
  申请人：LG CHEM, LTD.

  公开号：US20140066573A1

  公开（公告）日：2014-03-06

  Provided is a polymer preparing method. By additionally inputting a catalytic reducing agent that reduces an inactivated metal complex compound catalyst to an activated metal complex compound catalyst, a polymer polymerized at a high conversion ratio of a monomer can be provided.
• COMPOSITIONS OF POLYHYDROXYLATED BENZOPHENONES AND METHODS OF TREATMENT OF NEURODEGENERATIVE DISORDERS
  申请人：Massachusetts Institute of Technology

  公开号：US20200087236A9

  公开（公告）日：2020-03-19

  The present invention relates to polyhydroxylated benzophenone compounds useful in the treatment of neurodegenerative, neurological, psychiatric, and cognitive diseases, in particular those associated with a deficiency in HDAC1 deacetylase activity.
• US9090764B2
  申请人：——

  公开号：US9090764B2

  公开（公告）日：2015-07-28