fast blue B | 91-91-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: fast blue B
• 英文别名: 3,3'-dimethoxy-biphenyl-4,4'-bisdiazonium; chloride；3,3'-Dimethoxy-biphenyl-4,4'-bis-diazonium; Chlorid；3,3'-Dimethoxy-biphenyl-4,4'-bis-diazonium; Dichlorid；3,3'-dimethoxy(1,1'-biphenyl)-4,4'-bis(diazonium) dichloride；4,4'-bi(methoxybenzenediazonium chloride)；fast blue salt B；Diazo Blue B；4-(4-diazonio-3-methoxyphenyl)-2-methoxybenzenediazonium;chloride
• CAS: 91-91-8
• 化学式: C₁₄H₁₂N₄O₂*2Cl
• 分子量: 339.181
• InChiKey: LKOPEGAEYDVBMX-UHFFFAOYSA-M

物化性质

• 溶解度：
  超声处理轻微溶于甲醇，轻微溶于水

计算性质

• 辛醇/水分配系数(LogP)：
  1.34
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  74.8
• 氢给体数：
  0
• 氢受体数：
  5

安全信息

• 安全说明：
  S22,S24/25
• 危险类别码：
  R20/21
• 海关编码：
  2927000090

SDS

Azoic Diazo Component 48
SAFETY DATA SHEET

---

Section 1. IDENTIFICATION
Product name: Azoic Diazo Component 48

---

Section 2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDS Not classified
HEALTH HAZARDS
Acute toxicity (Oral) Category 4
Category 4
Acute toxicity (Dermal)
Acute toxicity (Inhalation) Category 4
Category 2
Skin corrosion/irritation
Serious eye damage/eye irritation Category 2A
Category 2
Germ cell mutagenicity
Reproductive toxicity Category 2
Liver, Respiratory system, Kidney, Lung, Pancreas
Specific target organ toxicity
- Single exposure [Category 1]
Respiratory tract irritation
Specific target organ toxicity
- Single exposure [Category 3]
Specific target organ toxicity Liver, Blood system, Lung, Adrenal gland
- Repeated exposure [Category 1]
ENVIRONMENTAL HAZARDS
Acute aquatic hazard Category 1
Long-term aquatic hazard Category 1
GHS label elements, including precautionary statements
Pictograms or hazard symbols
Signal word Danger
Harmful if swallowed, in contact with skin or if inhaled
Hazard statements
Causes skin irritation
Causes serious eye irritation
Suspected of causing genetic defects
Suspected of damaging fertility or the unborn child
Causes damage to organs : Liver Respiratory system Kidney
Lung Pancreas
Causes damage to organs through prolonged or repeated
exposure : Liver Blood system Lung Adrenal gland
Azoic Diazo Component 48

---

Section 2. HAZARDS IDENTIFICATION
May cause respiratory irritation
Very toxic to aquatic life
Very toxic to aquatic life with long lasting effects
Precautionary statements:
[Prevention] Obtain special instructions before use.
Do not handle until all safety precautions have been read and understood.
Do not breathe dust/fume/gas/mist/vapours/spray.
Use only outdoors or in a well-ventilated area.
Avoid release to the environment.
Do not eat, drink or smoke when using this product.
Wash hands thoroughly after handling.
Wear protective gloves and eye/face protection.
[Response] IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for
breathing. Call a POISON CENTER or doctor/physician if you feel unwell.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Rinse mouth.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF ON SKIN: Gently wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Wash contaminated clothing before reuse.
IF exposed or concerned: Get medical advice/attention.
Collect spillage.
Store in a well-ventilated place. Keep container tightly closed.
[Storage]
Store locked up.
[Disposal] Dispose of contents/container through a waste management company authorized by
the local government.

---

Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture: Substance
Components: Azoic Diazo Component 48
Percent: ....
91-91-8
CAS Number:
Synonyms: Diazo Blue B Salt , Fast Blue B Salt , Naphthanil Diazo Blue B Salt
Chemical Formula: C14H12Cl2N4O2·ZnCl2·ZnSO4

---

Section 4. FIRST AID MEASURES
Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention.
Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
Skin contact:
soap and water. Get medical advice/attention.
Rinse cautiously with water for several minutes. Remove contact lenses, if present
Eye contact:
and easy to do. Get medical advice/attention.
Get medical advice/attention.Rinse mouth.
Ingestion:
Protection of first-aiders: A rescuer should wear personal protective equipment, such as rubber gloves and air-
tight goggles.

---

Section 5. FIRE-FIGHTING MEASURES
Dry chemical, foam, water spray, carbon dioxide.
Suitable extinguishing
media:
Specific hazards arising Explosion risk in case of fire. Fight fire remotely due to the risk of explosion.
from the chemical: Take care as it may decompose upon combustion or in high temperatures to
generate poisonous fume.
Azoic Diazo Component 48

---

Section 5. FIRE-FIGHTING MEASURES
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Keep containers cool by
spraying with water. Eliminate all ignition sources if safe to do so.
Special protective When extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

---

Section 6. ACCIDENTAL RELEASE MEASURES
Use extra personal protective equipment (P3 filter respirator for toxic particles). Keep
Personal precautions,
protective equipment and people away from and upwind of spill/leak. Entry to non-involved personnel should
emergency procedures: be controlled around the leakage area by roping off, etc.
Environmental precautions: Be careful not to let it flow into rivers, etc., since adverse effects on the environment
are concerned.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

---

Section 7. HANDLING AND STORAGE
Precautions for safe handling
Technical measures: Handling is performed in a well ventilated place. Wear suitable protective equipment.
Be careful not to cause leakage, overflow, or dispersion. Steam should not be
generated unnecessarily. Keep away from heat/sparks/open flame/hot surfaces. -No
smoking. Take measures to prevent the build up of electrostatic charge. Use
explosion-proof equipment. Avoid shock and friction. Wash hands and face before
breaks and immediately after handling the product.
Use a closed system if possible. Use a local exhaust if dust or aerosol will be
generated.
Advice on safe handling: Avoid all contact!
Conditions for safe storage, including any
incompatibilities
Storage conditions: Keep container tightly closed. Store in a cool, dark and well-ventilated place.
Store locked up.
Be sure not to give the container unexpected impacts, such as falling down or falling
off.
Store away from incompatible materials such as oxidizing agents.
Comply with laws.
Packaging material:

---

Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls: Install a closed system or local exhaust. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator, self-contained breathing apparatus(SCBA), supplied air respirator,
etc. Use respirators approved under appropriate government standards and follow
local and national regulations.
Impervious gloves.
Hand protection:
Eye protection: Safety goggles. A face-shield, if the situation requires.
Skin and body protection: Impervious protective clothing. Protective boots, if the situation requires.

---

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C): Solid
Form: Crystal- Powder
Pale yellow - Greyish yellow red
Colour:
Odour: No data available
pH: No data available
Melting point/freezing point:No data available
Boiling point/range: No data available
Flash point: No data available
Azoic Diazo Component 48

---

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Flammability or explosive
limits:
Lower: No data available
Upper: No data available
Relative density: No data available
Solubility(ies):
[Water] No data available
No data available
[Other solvents]

---

Section 10. STABILITY AND REACTIVITY
Chemical stability: Stable under proper conditions.
Possibility of hazardous May explosively decompose on heating, shock, friction, etc.
reactions:
Conditions to avoid: Heat, Shock, Friction
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Sulfur oxides, Hydrogen
chloride
products:

---

Section 11. TOXICOLOGICAL INFORMATION
Acute Toxicity: No data available
Skin corrosion/irritation: No data available
Serious eye No data available
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
IARC = No data available
No data available
NTP =
Reproductive toxicity: No data available

---

Section 12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: No data available
Crustacea: No data available
Algae: No data available
Persistence / degradability: No data available
Bioaccumulative No data available
potential(BCF):
Mobility in soil
Log Pow: No data available
Soil adsorption (Koc): No data available
Henry's Law No data available
constant(PaM3/mol):

---

Section 13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities and an expert of disposal. You may be able
to dissolve or mix material with a combustible solvent and little by little burn in a chemical incinerator equipped with
an afterburner and scrubber system. If a large amount of the substance is burned at a time, an explosion may
occur. Observe all federal, state and local regulations when disposing of the substance.

---

Section 14. TRANSPORT INFORMATION
Hazards Class: 9: Miscellaneous dangerous goods.
UN-No: 3077
Proper shipping name: Environmentally hazardous substance, solid, n.o.s.
Packing group: III
Marine pollutant Y
Azoic Diazo Component 48

---

Section 15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

制备方法

组织化学中用于重氮化偶合反应，检定磷酸酯酶，纸色谱测定黄酮、胺和酚。0.5%水溶液可作显色剂，薄层色谱分析测定黄曲霉素，也可用作蛋白质染色剂。

用途简介

暂无相关信息。

用途

组织化学中用于重氮化偶合反应，检定磷酸酯酶，纸色谱测定黄酮、胺和酚。0.5%水溶液可作显色剂，薄层色谱分析测定黄曲霉素，也可用作蛋白质染色剂。

反应信息

• 作为反应物：
  描述：

  fast blue B 在 potassium iodide 作用下， 以70%的产率得到4,4'-diiodo-3,3'-dimethoxylbiphenyl
  参考文献：
  名称：

  New staves for old barrels: regioisomeric (1²,2²,3³,4²,5³,6²,7³,8²)-p-octiphenyl rods with an NMR tag

  摘要：

  该研究评估了具有新型 12,22,33,42,53,62,73,82 位点的刚杆对联辛基苯作为刚杆 β 桶状孔隙中的支柱的实用性。与具有 13,23,32,43,52,63,72,83 共序的异构体孔隙的已知特征进行比较后发现，硬杆 β-桶状孔隙的自组装和超分子手性与对辛基苯基支链的取代模式无关。图中显示了在杆末端添加的 NMR 标记，以方便产品表征。

  DOI：

  10.1039/b512276g
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 盐酸 、 titanium(III) chloride 作用下， 生成 fast blue B
  参考文献：
  名称：

  Knecht, Journal of the Chemical Society, 1924, vol. 125, p. 1538

  摘要：

  DOI：

文献信息

• Synthetic pores with sticky π-clamps
  作者：Hiroyuki Tanaka、Guillaume Bollot、Jiri Mareda、Svetlana Litvinchuk、Duy-Hien Tran、Naomi Sakai、Stefan Matile

  DOI：10.1039/b702255g

  日期：——

  In this report, we describe design, synthesis, evaluation and molecular dynamics simulations of synthetic multifunctional pores with π-acidic naphthalenediimide clamps. Experimental evidence is provided for the formation of unstable but inert, heterogeneous and acid-insensitive dynamic tetrameric pores that are sensitive to base and ionic strength. Blockage experiments reveal that the introduction of aromatic electron donor–acceptor interactions provides access to the selective recognition of π-basic intercalators within the pore. This breakthrough is important for the application of synthetic pores as multianalyte sensors.

  在本报告中，我们描述了具有π-酸性萘二酰亚胺夹具的合成多功能孔的设计、合成、评估和分子动力学模拟。实验证据表明，形成了不稳定但惰性、异质和抗酸动态四聚孔，这些孔对碱和离子强度敏感。阻塞实验揭示，引入芳香电子给体-接受体相互作用使得可以选择性识别孔内的π-碱性插层物。这一突破对于将合成孔应用于多分析物传感器具有重要意义。
• Rigid-rod push–pull naphthalenediimide photosystems
  作者：Naomi Sakai、Adam L. Sisson、Sheshanath Bhosale、Alexandre Fürstenberg、Natalie Banerji、Eric Vauthey、Stefan Matile

  DOI：10.1039/b708449h

  日期：——

  Design, synthesis and evaluation of advanced rigid-rod π-stack photosystems with asymmetric scaffolds are reported. The influence of push–pull rods on self-organization, photoinduced charge separation and photosynthetic activity is investigated and turns out to be surprisingly small overall.

  报告介绍了具有不对称支架的先进刚性杆Ï-叠层光系统的设计、合成和评估。研究了推拉杆对自组织、光诱导电荷分离和光合作用活性的影响，结果表明其总体影响之小令人惊讶。
• New staves for old barrels: regioisomeric (1²,2²,3³,4²,5³,6²,7³,8²)-p-octiphenyl rods with an NMR tag
  作者：Dawn Ronan、Damien Jeannerat、André Pinto、Naomi Sakai、Stefan Matile

  DOI：10.1039/b512276g

  日期：——

  The usefulness of rigid-rod p-octiphenyls with the novel 12,22,33,42,53,62,73,82-motif as staves in rigid-rod β-barrel pores is evaluated. Comparison with the known characteristics of isomeric pores with the common 13,23,32,43,52,63,72,83-sequence indicates that the self-assembly and the supramolecular chirality of rigid-rod β-barrels are independent of the substitution pattern of the p-octiphenyl stave. NMR tags added at the rod termini are shown to facilitate product characterization.

  该研究评估了具有新型 12,22,33,42,53,62,73,82 位点的刚杆对联辛基苯作为刚杆 β 桶状孔隙中的支柱的实用性。与具有 13,23,32,43,52,63,72,83 共序的异构体孔隙的已知特征进行比较后发现，硬杆 β-桶状孔隙的自组装和超分子手性与对辛基苯基支链的取代模式无关。图中显示了在杆末端添加的 NMR 标记，以方便产品表征。
• Ordered and Oriented Supramolecular n/p-Heterojunction Surface Architectures: Completion of the Primary Color Collection
  作者：Ravuri S. K. Kishore、Oksana Kel、Natalie Banerji、Daniel Emery、Guillaume Bollot、Jiri Mareda、Alberto Gomez-Casado、Pascal Jonkheijm、Jurriaan Huskens、Plinio Maroni、Michal Borkovec、Eric Vauthey、Naomi Sakai、Stefan Matile

  DOI：10.1021/ja9030648

  日期：2009.8.12

  and molecular modeling data on zipper assembly. Compared to the previously reported blue and red NDIs, yellow NDIs are more pi-acidic, easier to reduce, and harder to oxidize. The optoelectronic matching achieved in yellow POP-NDIs is reflected in quantitative and long-lived photoinduced charge separation, comparable to their red and much better than their blue counterparts. The direct comparison

  在本研究中，我们描述了黄色对低聚苯基萘二亚胺 (POP-NDI) 供体-受体杂化物的合成、表征和拉链组装。此外，我们首次公开了拉链和逐层（LBL）组装以及石英晶体微量天平（QCM）、原子力显微镜（AFM）和拉链分子建模数据的功能比较结果集会。与之前报道的蓝色和红色 NDI 相比，黄色 NDI 更酸，更容易还原，更难氧化。在黄色 POP-NDI 中实现的光电匹配反映在定量和长寿命的光致电荷分离上，可与红色相媲美，但比蓝色好得多。拉链和 LBL 组件的直接比较表明，黄色拉链比蓝色拉链和 LBL 光系统产生更多的光电流。在 QCM 测量中发现的持续线性增长表明，在关键组件厚度处发生光电流饱和是因为更多的电荷在到达电极之前开始重新组合，而不是因为组件中断。所发现的特性，例如显着的临界厚度、强光电流、大填充因子，以及根据 AFM 图像的光滑表面，对于光电性能很重要，并支持高度有序架构的存在。在 QCM
• 一种替代联苯胺制备直接染料的方法
  申请人：广东省科学院测试分析研究所（中国广州分析测试中心）

  公开号：CN116355434A

  公开（公告）日：2023-06-30

  本发明公开了一种替代联苯胺制备直接染料的方法。该方法是以2,7‑二氨基‑9‑芴酮替代3,3’‑二甲氧基联苯胺作为连接基团制备直接染料，制得的产物具有和联苯胺类直接染料化合物类似的光学性能。2,7‑二氨基‑9‑芴酮结构稳定、不易分解、不易吸收，安全低毒，可以替代联苯胺，实现简单有效地制备长吸收波长直接染料的目的。