[(2S,3R,4S,5R,6R)-3,4,5-tribenzoyloxy-6-[[tert-butyl(diphenyl)silyl]oxymethyl]oxan-2-yl] 4-hydroxybenzoate | 211947-42-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: [(2S,3R,4S,5R,6R)-3,4,5-tribenzoyloxy-6-[[tert-butyl(diphenyl)silyl]oxymethyl]oxan-2-yl] 4-hydroxybenzoate
• CAS: 211947-42-1
• 化学式: C₅₀H₄₆O₁₁Si
• 分子量: 850.994
• InChiKey: QZHLBBGXCLHDRK-GJPBNLNHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.53
• 重原子数：
  62
• 可旋转键数：
  18
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  144
• 氢给体数：
  1
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  phenyl 2-O-benzoyl-3,4,6-tri-O-benzyl-1-thio-β-D-glucopyranoside 、 [(2S,3R,4S,5R,6R)-3,4,5-tribenzoyloxy-6-[[tert-butyl(diphenyl)silyl]oxymethyl]oxan-2-yl] 4-hydroxybenzoate 、 [(2S,3R,4S,5R,6R)-6-[[tert-butyl(diphenyl)silyl]oxymethyl]-4-(9H-fluoren-9-ylmethoxycarbonyloxy)-2-methylsulfanyl-5-phenylmethoxyoxan-3-yl] benzoate 生成
  参考文献：
  名称：

  Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide

  摘要：

  Complicated oligosaccharides such as dodecasaccharide 1 can be constructed by a new solid-phase strategy. The attachment to the polymeric support (gray sphere) is through a photolabile linker (structure I), and thioglycosides serve as carbohydrate donors. Bn=benzyl, Bz=benzoyl.

  DOI：

  10.1002/(sici)1521-3773(19980619)37:11<1559::aid-anie1559>3.0.co;2-e
• 作为产物：
  描述：

  4-苯甲氧基苯甲酸 在 palladium on activated charcoal N-碘代丁二酰亚胺 、 三氟甲磺酸 、 甲酸铵 作用下， 以 四氢呋喃 、 甲醇 、 二氯甲烷 为溶剂， 反应 4.5h， 生成 [(2S,3R,4S,5R,6R)-3,4,5-tribenzoyloxy-6-[[tert-butyl(diphenyl)silyl]oxymethyl]oxan-2-yl] 4-hydroxybenzoate
  参考文献：
  名称：

  Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide

  摘要：

  Complicated oligosaccharides such as dodecasaccharide 1 can be constructed by a new solid-phase strategy. The attachment to the polymeric support (gray sphere) is through a photolabile linker (structure I), and thioglycosides serve as carbohydrate donors. Bn=benzyl, Bz=benzoyl.

  DOI：

  10.1002/(sici)1521-3773(19980619)37:11<1559::aid-anie1559>3.0.co;2-e

文献信息

• Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide
  作者：K. C. Nicolaou、Nobuhide Watanabe、Jim Li、Joaquín Pastor、Nicolas Winssinger

  DOI：10.1002/(sici)1521-3773(19980619)37:11<1559::aid-anie1559>3.0.co;2-e

  日期：1998.6.19

  Complicated oligosaccharides such as dodecasaccharide 1 can be constructed by a new solid-phase strategy. The attachment to the polymeric support (gray sphere) is through a photolabile linker (structure I), and thioglycosides serve as carbohydrate donors. Bn=benzyl, Bz=benzoyl.