nymphaeol B | 73676-37-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: nymphaeol B
• 英文别名: (2S)-2-[2-[(2E)-3,7-dimethylocta-2,6-dienyl]-3,4-dihydroxyphenyl]-5,7-dihydroxy-2,3-dihydrochromen-4-one
• CAS: 73676-37-6
• 化学式: C₂₅H₂₈O₆
• 分子量: 424.5
• InChiKey: ILCMVLORKWIOOH-CEMXSPGASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  31
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• New use of histone deacetylase inhibitors in changing MRJP3 protein in royal jelly
  申请人：NatureWise Biotech & Medicals Corporation

  公开号：EP2277387A1

  公开（公告）日：2011-01-26

  The invention provides a method of changing a ratio of 68 to 64 kDa protein of MRJP3 in a royal jelly, a method of producing a royal jelly comprising MRJP3 having a changed ratio of 68 to 64 kDa protein relative to a control royal jelly and the royal jelly produced thereform. Also provided is a method of promoting the growth of the larva of a queen bee comprising feeding the larva of the queen bee a royal jelly of the invention. Further provided is a method of producing bee larva, pupa and queen bees with sizes larger than normal.

  本发明提供了一种改变蜂王浆中MRJP3的68与64 kDa蛋白比例的方法，一种生产含有MRJP3的蜂王浆的方法，相对于对照蜂王浆，MRJP3的68与64 kDa蛋白比例发生了改变，并以这种方法生产出蜂王浆。还提供了一种促进蜂王幼虫生长的方法，包括给蜂王幼虫喂食本发明的蜂王浆。此外，还提供了一种生产蜂王幼虫、蛹和蜂王的方法，其蜂王幼虫、蛹和蜂王的尺寸大于正常尺寸。
• Prenylflavanone compounds for modulating diabetes
  申请人：NatureWise Biotech & Medicals Corporation

  公开号：EP2783684A1

  公开（公告）日：2014-10-01

  The present invention is directed to a novel use of prenylflavanone compounds for control of blood glucose and treatment or prevention of diabetes.

  本发明涉及一种控制血糖和治疗或预防糖尿病的前黄烷酮化合物的新用途。
• NEW USE OF HISTONE DEACETYLASE INHIBITORS IN CHANGING MRJP3 PROTEIN IN ROYAL JELLY
  申请人：NatureWise Biotech & Medicals Corporation

  公开号：EP2277387B1

  公开（公告）日：2016-10-19
• PRENYLFLAVANONE COMPOUNDS FOR MODULATING DIABETES
  申请人：NatureWise Biotech & Medicals Corporation

  公开号：EP2783684B1

  公开（公告）日：2018-10-03
• BENZENE COMPOUNDS FOR TREATING OCULAR DISEASES
  申请人：NatureWise Biotech & Medicals Corporation

  公开号：EP3261635B1

  公开（公告）日：2021-03-31