1-(4-Isopropylphenyl)-1H-pyrazole-4-carbaldehyde | 1015845-83-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(4-Isopropylphenyl)-1H-pyrazole-4-carbaldehyde
• 英文别名: 1-(4-propan-2-ylphenyl)pyrazole-4-carbaldehyde
• CAS: 1015845-83-6
• 化学式: C₁₃H₁₄N₂O
• mdl: MFCD08691536
• 分子量: 214.26
• InChiKey: WNMZTFXCGJBJIV-UHFFFAOYSA-N

物化性质

• 沸点：
  335.3±25.0 °C(Predicted)
• 密度：
  1.09±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  34.9
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 危险性防范说明：
  P264,P280,P302+P352,P337+P313,P305+P351+P338,P362+P364,P332+P313
• 危险性描述：
  H315,H319

文献信息

• NOVEL COMPOUND AS MTOR INHIBITOR AND USE THEREOF
  申请人：Medicinal Bioconvergence Research Center

  公开号：EP3786163A1

  公开（公告）日：2021-03-03

  The present invention relates to a novel compound as an mTOR inhibitor and a use thereof and, more specifically, to a novel compound represented by formula 1 that exhibits mTOR inhibitory activity and a pharmaceutical composition comprising same as an active ingredient for preventing or treating brain diseases associated with an mTOR pathway.

  本发明涉及一种作为mTOR抑制剂的新化合物及其用途，更具体地，涉及一种由式1表示的新化合物，该化合物表现出mTOR抑制活性，并且包括该化合物作为活性成分的药物组合物，用于预防或治疗与mTOR途径相关的脑疾病。
• NOVEL COMPOUND AS mTOR INHIBITOR AND USE THEREOF
  申请人：MEDICINAL BIOCONVERGENCE RESEARCH CENTER

  公开号：US20210292314A1

  公开（公告）日：2021-09-23

  The present invention relates to a novel compound as an mTOR inhibitor and a use thereof and, more specifically, to a novel compound represented by formula 1 that exhibits mTOR inhibitory activity and a pharmaceutical composition comprising same as an active ingredient for preventing or treating brain diseases associated with an mTOR pathway.