Dimethyl 3-(glycylamino)pentanedioate | 141340-89-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 肽模拟物
• 英文名称: Dimethyl 3-(glycylamino)pentanedioate
• 英文别名: dimethyl 3-[(2-aminoacetyl)amino]pentanedioate
• CAS: 141340-89-8
• 化学式: C₉H₁₆N₂O₅
• 分子量: 232.23
• InChiKey: XGPCVWORKWFCRW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  16
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  108
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Integrated Photoactive Small Molecules and Uses Thereof
  申请人：Neumann William L.

  公开号：US20100105899A1

  公开（公告）日：2010-04-29

  This invention is directed to the general method of transforming non-photoactive bioactive small molecule compounds of known structure and function into photoactive analogs of the small molecules which exhibit both photoactivity and the original biological targeting activity. The general method for the design of the photoactive analogs of the small molecules includes: (a) selecting a desired bioactive molecule; (b) identifying the region of the molecule that contains an aromatic or a heteroaromatic motif; and (c) either replacing said motif with a photoactive functional group of similar size, or modifying said motif to make it photoactive. Other aspects include photoactive analog compounds and photodiagnostic and phototherapeutic uses thereof.