| 1092461-41-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• CAS: 1092461-41-0
• 化学式: C₁₇H₁₇NO₃
• 分子量: 283.327
• InChiKey: IUVOIXRJFOUFQG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  21.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  64.71
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  在 Lindlar's catalyst 喹啉 、 氢气 作用下， 以 甲醇 为溶剂， 以83%的产率得到
  参考文献：
  名称：

  Synthesis of photoaffinity probe based on the leaf-opening factor from genus Albizzia

  摘要：

  The circadian rhythmic leaf-movements in legumes, called nyctinasty, are regulated by a pair of leaf-closing and -opening factors. Recent fluorescence studies revealed that cis-p-coumaroylagmatine (1), the leaf-opening factor from genus Albizzia, specifically bound to motor cells in a joint of leaf and stem. in order to identify the receptor protein, which is expected to be involved in the plasma membrane of the cell, we designed and synthesized a photoaffinity probe (2), containing a photoreactive azide group on the aromatic ring and FLAG segment as a peptide antigen for immunoprecipitation. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.04.002
• 作为产物：
  描述：

  在 sodium dithionite 作用下， 以 丙酮 为溶剂， 以58%的产率得到
  参考文献：
  名称：

  Synthesis of photoaffinity probe based on the leaf-opening factor from genus Albizzia

  摘要：

  The circadian rhythmic leaf-movements in legumes, called nyctinasty, are regulated by a pair of leaf-closing and -opening factors. Recent fluorescence studies revealed that cis-p-coumaroylagmatine (1), the leaf-opening factor from genus Albizzia, specifically bound to motor cells in a joint of leaf and stem. in order to identify the receptor protein, which is expected to be involved in the plasma membrane of the cell, we designed and synthesized a photoaffinity probe (2), containing a photoreactive azide group on the aromatic ring and FLAG segment as a peptide antigen for immunoprecipitation. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.04.002