4-(dimethylamino)-1,5-dimethyl-2-phenylpyrazol-3-one;N-(4-ethoxyphenyl)acetamide | 8066-72-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-(dimethylamino)-1,5-dimethyl-2-phenylpyrazol-3-one;N-(4-ethoxyphenyl)acetamide
• CAS: 8066-72-6
• 化学式: C23H30N4O3
• 分子量: 410.5
• InChiKey: IYHHPTMCLZBREU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.59
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  65.1
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• USE OF ORGANIC DYES AS ANALGESIC AGENTS
  申请人：Kutushov Mikhail Vladimirovich

  公开号：US20120122966A1

  公开（公告）日：2012-05-17

  An organic dye from the group of crystal violet, gentian violet, malachite green oxalate and rhodamine 6G used as an analgesic agent in the form of a solution with the agent dosage ranging from 0.000001 mg to 10 g per intake. It is preferable to take the agent at least two times a day. In particular cases of use the agent is administered by mouth in the form of an aqueous solution before or after meals, or it is administered per rectum in the form of an aqueous solution, or a 1% solution of the agent is administered intravenously, or the agent is used in the form of a 1-5% ointment, or the agent is administered per rectum in the form of suppositories, and when arresting cancer pain the agent is injected into the tumor (under the tumor) or into a metastasis. Herein, one uses as analgesic agents widely available and inexpensive substances that are non-toxic, have no allergic effects and cause no addiction (dependence) when used in pharmaceutically acceptable doses; the treatment time is reduced, treatment efficiency is enhanced, and pain relief is provided while preserving patients' functional activity, using the minimum arsenal of analgesic agents with different effects, and completely eliminating the need for opiates.