3-氰基-2-二乙基氨基吡啶 | 17782-02-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 3-氰基-2-二乙基氨基吡啶
• 英文名称: 2-diethylamino-nicotinonitrile
• 英文别名: 3-Cyano-2-diethylaminopyridine；2-(diethylamino)pyridine-3-carbonitrile
• CAS: 17782-02-4
• 化学式: C₁₀H₁₃N₃
• mdl: MFCD09896569
• 分子量: 175.233
• InChiKey: QMYGNXYWTWFBRY-UHFFFAOYSA-N

物化性质

• 沸点：
  295.5±25.0 °C(Predicted)
• 密度：
  1.06±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  39.9
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 危险等级：
  IRRITANT
• 海关编码：
  2933399090

SDS

3-氰基-2-二乙基氨基吡啶MSDS英文版

反应信息

• 作为产物：
  描述：

  吡啶-2,3-二甲腈 、 二乙胺 以 乙腈 为溶剂， 反应 4.0h， 生成 3-氰基吡啶 、 3-氰基-2-二乙基氨基吡啶 、 3-Diethylamino-pyridine-2-carbonitrile
  参考文献：
  名称：

  Bernardi, Rosanna; Caronna, Tullio; Poggi, Gabriella, Journal of Heterocyclic Chemistry, 1994, vol. 31, # 4, p. 903 - 908

  摘要：

  DOI：

文献信息

• Method with separation and kit for use in the method
  申请人：PHARMACIA DIAGNOSTICS AB

  公开号：EP1467210A1

  公开（公告）日：2004-10-13

  The invention relates to a method for determining the binding capability of a structure (ligand) to an analyte, which method comprises: i. applying the sample to an application zone for sample (ASZ) on a flow matrix in which transport of components present in the sample may take place (transport flow), the flow matrix further comprising: a) optionally an application zone (AR*Z) for a binding reactant (Reactant* = R*) which is analytically detectable, b) a detection zone (DZ) which is located downstream of ASZ and comprises another binding reactant (Capturer) firmly anchored to the matrix and in which a complex (signal complex) containing the Capturer and the analyte and/or Reactant* is formed during the method, and ii. detecting the signal complex in the detection zone, the measured signal being used for determining the analyte, wherein the flow matrix comprises at least one separation zone (SZ) between ASZ and DZ and this zone (SZ) exhibits a structure (ligand) having binding capability for the analyte, and the binding capability of the ligand for the analyte is determined. According to the invention, the flow matrix comprises at least one separation zone (SZ) between ASZ and DZ, which zone exhibits a structure (ligand) having binding capability for the analyte that is transported in the matrix. The invention also relates to a test kit comprising the flow matrix.

  本发明涉及一种确定结构（配体）与分析物结合能力的方法，该方法包括 i. 将样品应用于流动基质上的样品应用区（ASZ），样品中的成分可在该应用区中发生迁移（迁移流），流动基质进一步包括： ii： a) 可选的结合反应物（反应物* = R*）应用区（AR*Z），该反应物可进行分析检测、 b) 位于 ASZ 下游的检测区 (DZ)，该检测区包含牢固固定在基质上的另一种结合反应物（捕获剂），在该方法中会形成包含捕获剂和被分析物和/或反应物*的复合物（信号复合物），以及 ii. 在检测区检测信号复合物，检测到的信号用于确定被分析物、 其中，流动基质包括 ASZ 和 DZ 之间的至少一个分离区 (SZ)，该分离区 (SZ) 显示出与被分析物具有结合能力的结构（配体），并确定配体与被分析物的结合能力。根据本发明，流动基质包括 ASZ 和 DZ 之间的至少一个分离区 (SZ)，该分离区显示的结构（配体）具有与基质中传输的分析物结合的能力。本发明还涉及一种包含流动基质的检测试剂盒。
• LIGAND BINDING ASSAY AND KIT WITH A SEPARATION ZONE FOR DISTURBING SAMPLE COMPONENTS
  申请人：MAIIA AB

  公开号：EP1075661B1

  公开（公告）日：2007-08-22
• LIGAND BINDING ASSAY AND KIT WITH A SEPARATION ZONE FOR DISTURBING ANALYTES
  申请人：PHARMACIA AB

  公开号：EP1075661A1

  公开（公告）日：2001-02-14
• Ligand binding assay and kit with a separation zone for disturbing analytes
  申请人：Pharmacia & Upjohn Diagnostics AB.

  公开号：US20040023412A1

  公开（公告）日：2004-02-05

  The invention relates to method for determining an analyte by means of binding reactions, which method comprises: i) applying the sample to an application zone for sample (ASZ) on a flow matrix in which transport of components present in the sample can take place (transport flow), the flow matrix further exhibiting: a) optionally an application zone (AR*Z) for a binding reactant (Reactant*=R*) which is analytically detectable; b) a detection zone (DZ), which is located downstream of ASZ and exhibits an additional binding reactant (Capturer) firmly anchored to the matrix, and in which a complex (signal complex) containing the Capturer and the analyte and/or Reactant* is formed during the reaction, and ii) detecting the signal complex in the detection zone, the measured signal being used for determining the analyte. According to the invention, the flow matrix comprises at least one separation zone (SZ) between ASZ and DZ, which zone exhibits a structure (ligand) having binding capability for a component that is transported in the matrix and which would affect the measurable signal if the component is transported into DZ. The invention also relates to a test kit comprising the flow matrix.
• US6737278B1
  申请人：——

  公开号：US6737278B1

  公开（公告）日：2004-05-18