3-溴-1-戊烯 | 53045-71-9

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机溴化物
• 中文名称: 3-溴-1-戊烯
• 英文名称: 3-bromo-1-pentene
• 英文别名: 3-bromopent-1-ene；1-Pentene, 3-bromo-
• CAS: 53045-71-9
• 化学式: C₅H₉Br
• 分子量: 149.03
• InChiKey: MAUHKVNIHVSMSP-UHFFFAOYSA-N

物化性质

• 熔点：
  -106.7°C (estimate)
• 沸点：
  114.3°C (estimate)
• 密度：
  1.2200

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  6
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 海关编码：
  2903399090

反应信息

• 作为反应物：
  描述：

  3-溴-1-戊烯 以 甲醇 为溶剂， 反应 92.75h， 生成 3',3'-Dimethyl-6-nitro-1'-pent-4-enylspiro[chromene-2,2'-indole]
  参考文献：
  名称：

  Synthesis and characterisation of polymerisable photochromic spiropyrans: towards photomechanical biomaterials

  摘要：

  A methodology for the synthesis of novel polymerisable spiropyrans with photomechanical properties suitable for subsequent copolymerisation with either vinyl or acrylate-based biomaterials is described. UV-vis spectroscopic characterisation of photoisomerism shows that photochromic behaviour with respect to related non-polymerisable compounds is retained and is solvent dependent. In acetone, conventional spiropyran-merocyanine photochromism is observed for nitro-spiropyran derivatives, whereas in dichloromethane both nitro-spiropyrans and spiropyrans isomerise to merocyanines which rapidly form H-aggregates. The monomers were designed such that an alkyl spacer of variable length, both electronically and sterically, separates the polymerisable moiety from the photochromic core and allows steric aspects of the resulting photomechanical behaviour to be explored. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.11.110
• 作为产物：
  描述：

  1-戊烯-3-醇 在 吡啶 、 三溴化磷 作用下， 以 乙醚 为溶剂， 反应 2.0h， 以7%的产率得到3-溴-1-戊烯
  参考文献：
  名称：

  Attractant pheromones of coleoptera. Communication 1. Simple synthesis of exo- and endo-brevicomins using the oxy-cope rearrangement

  摘要：

  DOI：

  10.1007/bf00948528

文献信息

• Preparation of cyclic imides from alkene-tethered amides: application of homogeneous Cu(<scp>ii</scp>) catalytic systems
  作者：Zhenghui Liu、Peng Wang、Hualin Ou、Zhenzhong Yan、Suqing Chen、Xingxing Tan、Dongkun Yu、Xinhui Zhao、Tiancheng Mu

  DOI：10.1039/c9ra10422d

  日期：——

  A Cu-based homogeneous catalytic system was proposed for the preparation of imides from alkene-tethered amides. Here, O2 acted as a terminal oxidant and a cheap and easily available oxygen source. The cleavage of CC bonds and the formation of C–N bonds were catalyzed by Cu(II) salts with proper nitrogen-containing ligands under 100 °C. The synthesis approach has potential applications in pharmaceutical

  提出了一种基于铜的均相催化体系，用于从烯烃束缚酰胺制备酰亚胺。在这里，O 2充当末端氧化剂和廉价且容易获得的氧源。在 100 °C 下，具有适当含氮配体的 Cu( II ) 盐催化C C 键的断裂和 C-N 键的形成。该合成方法在药物合成中具有潜在的应用。此外，放大实验证实了实际适用性。
• Vitamin D derivative with substituent at the 2.beta.-position
  申请人：Chugai Seiyaku Kabushiki Kaisha

  公开号：US05877168A1

  公开（公告）日：1999-03-02

  A 1.alpha.-hydroxy-vitamin D derivative represented by formula (I): ##STR1## wherein R.sub.1 represents a hydrogen atom or a hydroxyl group; and R.sub.2 represents a straight-chain or branched lower alkyl, lower alkenyl or lower alkynyl group, which is substituted with a hydroxyl group, a halogen atom, a cyano group, a lower alkoxy group, an amino group or an acylamino group, is disclosed. The compound exhibits calcium metabolism regulating activity and differentiation stimulating activity on tumor cells, etc. and is useful as a treating agent for diseases caused by abnormal calcium metabolism, such as osteoporosis and osteomalacia, or as an antitumor agent.

  一种由公式（I）表示的α-羟基维生素D衍生物：##STR1##其中R.sub.1代表氢原子或羟基基团；R.sub.2代表直链或支链低级烷基，低级烯基或低级炔基，其被羟基基团，卤素原子，氰基，低级烷氧基，氨基或酰胺基取代，该化合物表现出调节钙代谢和刺激肿瘤细胞分化等活性，并可用作治疗因异常钙代谢引起的疾病，如骨质疏松和软骨病，或作为抗肿瘤剂。
• Total Synthesis of (−)-trans-Kumausyne
  作者：K Osumi

  DOI：10.1016/00404-0399(50)1100v-

  日期：1995.8.7

  The total synthesis of (-)-trans-kumausyne has been accomplished in an enantiospecific fashion starting from an L-arabinose derivative. The key step is the stereoselective formation of the substituted tetrahydrofuran via novel cyclization of the beta-silyl cation intermediate, generated by the addition of allylsilane to di-O-isopropylidene-aldehydo-arabinose in the presence of boron trifluoride etherate.
• Synthesis and characterisation of polymerisable photochromic spiropyrans: towards photomechanical biomaterials
  作者：Colin P. McCoy、Louise Donnelly、David S. Jones、Sean P. Gorman

  DOI：10.1016/j.tetlet.2006.11.110

  日期：2007.1

  A methodology for the synthesis of novel polymerisable spiropyrans with photomechanical properties suitable for subsequent copolymerisation with either vinyl or acrylate-based biomaterials is described. UV-vis spectroscopic characterisation of photoisomerism shows that photochromic behaviour with respect to related non-polymerisable compounds is retained and is solvent dependent. In acetone, conventional spiropyran-merocyanine photochromism is observed for nitro-spiropyran derivatives, whereas in dichloromethane both nitro-spiropyrans and spiropyrans isomerise to merocyanines which rapidly form H-aggregates. The monomers were designed such that an alkyl spacer of variable length, both electronically and sterically, separates the polymerisable moiety from the photochromic core and allows steric aspects of the resulting photomechanical behaviour to be explored. (c) 2006 Elsevier Ltd. All rights reserved.
• Attractant pheromones of coleoptera. Communication 1. Simple synthesis of exo- and endo-brevicomins using the oxy-cope rearrangement
  作者：�. P. Serebryakov、G. D. Gamalevich、R. I. Shekhtman

  DOI：10.1007/bf00948528

  日期：1985.8