| 1332504-79-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 1332504-79-6
• 化学式: C₄₆H₅₆F₃NO₈
• 分子量: 807.948
• InChiKey: IVNFZMSODADPOG-OXTBZDEWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.74
• 重原子数：
  58.0
• 可旋转键数：
  25.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  93.71
• 氢给体数：
  1.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  在 palladium on activated charcoal 、 氢气 、 溶剂黄146 作用下， 20.0 ℃ 、413.69 kPa 条件下， 反应 60.0h， 以91%的产率得到8-trifluoroacetamido-octyl 6-O-methyl-D-glycero-α-L-gluco-heptopyranoside
  参考文献：
  名称：

  Synthesis of the 6-O-Methyl-d-glycero-α-l-gluco-heptopyranose Moiety Present in the Capsular Polysaccharide from Campylobacter jejuni NCTC 11168

  摘要：

  The first synthesis of the 6-O-methyl-D-glycero-alpha-L-gluco-heptopyranose moiety present in the capsular polysaccharide from Campylobacter jejuni NCTC 11168 is reported. The target (1) was synthesized as the 8-aminooctyl glycoside and then conjugated to bovine serum albumin (BSA) for the generation of antibodies recognizing this motif. Heptose 1 was obtained from D-galactose via a series of galactofuranose derivatives.

  DOI：

  10.1021/ol202152r
• 作为产物：
  描述：

  C₃₈H₄₀Cl₃NO₇ 在 吡啶 、 三氟甲磺酸三甲基硅酯 、 palladium on activated charcoal 、 氢气 作用下， 以 乙醚 为溶剂， 反应 38.75h， 生成
  参考文献：
  名称：

  Synthesis of the 6-O-Methyl-d-glycero-α-l-gluco-heptopyranose Moiety Present in the Capsular Polysaccharide from Campylobacter jejuni NCTC 11168

  摘要：

  The first synthesis of the 6-O-methyl-D-glycero-alpha-L-gluco-heptopyranose moiety present in the capsular polysaccharide from Campylobacter jejuni NCTC 11168 is reported. The target (1) was synthesized as the 8-aminooctyl glycoside and then conjugated to bovine serum albumin (BSA) for the generation of antibodies recognizing this motif. Heptose 1 was obtained from D-galactose via a series of galactofuranose derivatives.

  DOI：

  10.1021/ol202152r