4-chloro-2-fluoro-5-isopropoxybenzyl alcohol | 188424-92-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 4-chloro-2-fluoro-5-isopropoxybenzyl alcohol
• 英文别名: 4-Chloro-2-fluoro-5-isopropoxybenzylalcohol；(4-chloro-2-fluoro-5-propan-2-yloxyphenyl)methanol
• CAS: 188424-92-2
• 化学式: C₁₀H₁₂ClFO₂
• 分子量: 218.655
• InChiKey: FRNZPDAAUZZGEP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-chloro-2-fluoro-5-isopropoxybenzyl alcohol 在 吡啶 、 氯化亚砜 作用下， 以 四氢呋喃 为溶剂， 生成 4-chloro-2-fluoro-5-isopropoxybenzyl chloride
  参考文献：
  名称：

  Pyrimidin-4-one derivatives, their intermediates for their production

  摘要：

  提供了式[1]的新型嘧啶-4-酮衍生物，其可作为除草剂的活性成分。其中，R.sup.1为氢或烷基；R.sup.2为烷基，可选用卤素取代；R.sup.3为烷基，可选用卤素、烯基或炔基取代；Q为取代苯基。同时提供了其中间体的生产方法和生产这些中间体的过程。

  公开号：

  US06100257A1
• 作为产物：
  描述：

  4-chloro-2-fluoro-5-isopropoxybenzaldehyde 在 盐酸 、 sodium borohydrid 作用下， 以 1,4-二氧六环 、 甲醇 为溶剂， 生成 4-chloro-2-fluoro-5-isopropoxybenzyl alcohol
  参考文献：
  名称：

  Pyrimidin-4-one derivatives, their intermediates for their production

  摘要：

  提供了式[1]的新型嘧啶-4-酮衍生物，其可作为除草剂的活性成分。其中，R.sup.1为氢或烷基；R.sup.2为烷基，可选用卤素取代；R.sup.3为烷基，可选用卤素、烯基或炔基取代；Q为取代苯基。同时提供了其中间体的生产方法和生产这些中间体的过程。

  公开号：

  US06100257A1

文献信息

• Pyridone derivatives and herbicides
  申请人：Kumiai Chemical Industry Co., Ltd.

  公开号：US06048823A1

  公开（公告）日：2000-04-11

  A pyridone derivative represented by the general formula: ##STR1## wherein R is an alkyl group or a haloalkyl group, R.sup.1 is a hydrogen atom, an alkyl group, a haloalkyl group, an acetyl group, an amino group, an alkoxycarbonylamino group, an alkylcarbonylamino group or the like, R.sup.2 is a hydrogen atom, an alkyl group, a carboxyl group or an alkoxycarbonyl group, R.sup.19 is a hydrogen atom, a halogen atom, a cyano group or the like, Q is a phenyl group which may be substituted or a condensed hetero ring which may be substituted}, a herbicide containing it and an intermediate for its production, are provided.

  由一般式表示的吡啶酮衍生物：##STR1## 其中R是烷基或卤代烷基，R.sup.1是氢原子、烷基、卤代烷基、乙酰基、氨基、烷氧羰基氨基、烷基羰基氨基等，R.sup.2是氢原子、烷基、羧基或烷氧羰基，R.sup.19是氢原子、卤素原子、氰基等，Q是苯基或可被取代的缩合杂环环，提供了含有它的除草剂及其生产中间体。
• Pyrimidin-4-one derivatives, their use, intermediates for their production, and processes for producing these intermediates
  申请人：Sumitomo Chemical Company, Limited

  公开号：US06242634B1

  公开（公告）日：2001-06-05

  Novel pyrimidin-4-one derivatives of formula [1] are provided, which are useful as active ingredients of herbicides, wherein R1 is hydrogen or alkyl; R2 is alkyl optionally substituted with halogen; R3 is alkyl optionally substituted with halogen, alkenyl, or alkynyl; and Q is substituted phenyl. Also provided are intermediates for their production and processes for producing these intermediates.

  提供了式子[1]的新型嘧啶-4-酮衍生物，其作为除草剂的活性成分是有用的，其中R1是氢或烷基；R2是烷基，可选地被卤素取代；R3是烷基，可选地被卤素、烯基或炔基取代；而Q是取代苯基。还提供了它们的中间体以及生产这些中间体的过程。
• PYRIDONE DERIVATIVES AND HERBICIDES
  申请人：KUMIAI CHEMICAL INDUSTRY CO., LTD.

  公开号：EP0885885A1

  公开（公告）日：1998-12-23

  A pyridone derivative represented by the general formula: wherein R is an alkyl group or a haloalkyl group, R1 is a hydrogen atom, an alkyl group, a haloalkyl group, an acetyl group, an amino group, an alkoxycarbonylamino group, an alkylcarbonylamino group or the like, R2 is a hydrogen atom, an alkyl group, a carboxyl group or an alkoxycarbonyl group, R19 is a hydrogen atom, a halogen atom, a cyano group or the like, Q is a phenyl group which may be substituted or a condensed hetero ring which may be substituted}, a herbicide containing it and an intermediate for its production, are provided. The herbicide of the present invention exhibits excellent herbicidal effects against various weeds which cause trouble in upland fields, for example, broad leaved weeds such as pale smartweed, slender amaranth, common lambsquaters, common chickweed, velvetleaf, prickly sida, hemp sesbania, pitted morningglory and common cocklebur, perennial and annual cyperaceous weeds such as purple nutsedge, yellow nutsedge, Cyperus brevifolius and rice flatsedge, and gramineous weeds such as barnyardgrass, Digitaria ciliaris, green foxtail, annual bluegrass, Johnsongrass, blackgrass and wild oat, over a wide range from the pre-germination to the growing stage. The herbicide of the present invention can further control annual paddy weeds such as barnyardgrass, smallflower umbrellaplant and monochoria and perennial paddy weeds such as Japanese ribbon wapato, arrowhead, flat sedge, water chestnut, bulrush and narrowleaf waterplantain. On the other hand, the herbicide of the present invention is highly safe to crop plants and shows high safety especially to rice, wheat, barley, corn, sorghum, soybean, cotton and sugar beet.

  由通式代表的吡啶酮衍生物： 其中 R 是烷基或卤代烷基，R1 是氢原子、烷基、卤代烷基、乙酰基、氨基、烷氧基羰基氨基、烷基羰基氨基或类似基团，R2 是氢原子、烷基、羧基或烷氧基羰基，R19 是氢原子、卤素原子、氰基或类似基团，Q 是苯基或类似基团、R19 是氢原子、卤素原子、氰基或类似基团，Q 是可被取代的苯基或可被取代的缩合杂环}，本发明提供了含有这些基团的除草剂及其生产中间体。 本发明的除草剂对各种给高地田带来麻烦的杂草有很好的除草效果，例如，阔叶杂草，如苍耳草、纤细苋、普通羔羊草、普通鸡冠花、绒毛草、刺五加、麻矢车菊、洼地牵牛花和普通鸡冠花、多年生和一年生禾本科杂草，如紫花地丁、黄花地丁、香附子和稻飞虱，以及禾本科杂草，如稗草、Digitaria ciliaris、绿狐尾、一年生蓝草、约翰逊草、黑穗禾和野燕麦。本发明的除草剂还能进一步防除一年生水稻杂草，如稗草、小花伞草和芒草，以及多年生水稻杂草，如日本带状禾本科杂草、箭杆草、平莎草、荸荠、牛筋草和狭叶水田芥。 另一方面，本发明的除草剂对作物植物非常安全，尤其是对水稻、小麦、大麦、玉米、高粱、大豆、棉花和甜菜。
• PYRIMIDIN-4-ONE DERIVATIVES, THEIR USE AS HERBICIDES, INTERMEDIATES FOR THEIR PRODUCTION AND PROCESSES FOR PRODUCING THESE COMPOUNDS
  申请人：SUMITOMO CHEMICAL COMPANY LIMITED

  公开号：EP0850229A1

  公开（公告）日：1998-07-01
• US6048823A
  申请人：——

  公开号：US6048823A

  公开（公告）日：2000-04-11