3-Amyl-1,2,4-triazol-5-on | 937-67-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3-Amyl-1,2,4-triazol-5-on
• 英文别名: 5-pentyl-2,4-dihydro-[1,2,4]triazol-3-one；3-Pentyl-1,4-dihydro-1,2,4-triazol-5-one
• CAS: 937-67-7
• 化学式: C₇H₁₃N₃O
• 分子量: 155.2
• InChiKey: JJUVRPUQWCSJFR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  53.5
• 氢给体数：
  2
• 氢受体数：
  1

文献信息

• Substituted Arylimidazolone and Triazolone as Inhibitors of Vasopressin Receptors
  申请人：Meier Heinrich

  公开号：US20090312381A1

  公开（公告）日：2009-12-17

  The present application relates to novel, substituted 4-arylimidazol-2-ones and 5-aryl-1,2,4-triazolones, processes for the production thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases and the use thereof for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.

  本申请涉及新颖的取代的4-芳基咪唑-2-酮和5-芳基-1,2,4-三唑酮，其生产方法，单独或组合使用以治疗和/或预防疾病，以及用于生产治疗和/或预防疾病的药物，特别是用于治疗和/或预防心血管疾病。
• TRIAZOLE DERIVATIVES AS VASOPRESSIN-RECEPTOR INHIBITORS FOR TREATING CARDIAC INSUFFICIENCY
  申请人：Brüggemeier Ulf

  公开号：US20120053218A1

  公开（公告）日：2012-03-01

  The present application relates to novel substituted phenylalanine derivatives, to processes for preparing them, to their use alone or in combinations for the treatment and/or prevention of diseases and also to their use for the production of medicaments for the treatment and/or prevention of diseases, more particularly for the treatment and/or prevention of cardiovascular disorders.

  本申请涉及新颖的取代苯丙氨酸衍生物，以及用于制备它们的方法，它们单独或组合用于治疗和/或预防疾病，还用于生产用于治疗和/或预防疾病的药物，更具体地用于治疗和/或预防心血管疾病。
• Heterocyclic-substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof
  申请人：Fürstner Chantal

  公开号：US20120208852A1

  公开（公告）日：2012-08-16

  The present application relates to new, heterocyclyl-substituted 2-acetamido-5-aryl-1,2,4-triazolones, to processes for preparing them, to their use alone or in combinations for the treatment and/or prevention of diseases and also to their use for the production of medicaments for the treatment and/or prevention of diseases, more particularly for the treatment and/or prevention of cardiovascular disorders.

  本申请涉及新的、杂环基取代的2-乙酰胺基-5-芳基-1,2,4-三唑酮，以及其制备方法，单独或组合用于治疗和/或预防疾病的用途，还涉及其用于生产治疗和/或预防疾病的药物，特别是用于治疗和/或预防心血管疾病。
• SUBSTITUTED ARYLIMIDAZOLONE AND TRIAZOLONE AS INHIBITORS OF VASOPRESSIN RECEPTORS
  申请人：Meier Heinrich

  公开号：US20130005704A1

  公开（公告）日：2013-01-03

  The present application relates to novel, substituted 4-arylimidazol-2-ones and 5-aryl-1,2,4-triazolones, processes for the production thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases and the use thereof for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.

  本申请涉及新型取代的4-芳基咪唑-2-酮和5-芳基-1,2,4-三唑酮，其生产过程，其单独或联合用于治疗和/或预防疾病的用途以及用于生产用于治疗和/或预防疾病的药物的用途，特别是用于治疗和/或预防心血管疾病。
• HALOALKYL TRIAZOLINONES
  申请人：FMC Corporation

  公开号：EP0221083A1

  公开（公告）日：1987-05-13