Naringin [10236-47-2]

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: Naringin [10236-47-2]
• 英文别名: 7-[(2S,4R,5S)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,4S,5R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
• 化学式: C₂₇H₃₂O₁₄
• 分子量: 580.5
• InChiKey: DFPMSGMNTNDNHN-CSBXLKJISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  41
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  225
• 氢给体数：
  8
• 氢受体数：
  14

文献信息

• NOVEL FLAVONE GLYCOSIDE DERIVATIVES FOR USE IN COSMETICS, PHARMACEUTICALS AND NUTRITION
  申请人：Geers Bernadette

  公开号：US20080176811A1

  公开（公告）日：2008-07-24

  Substituted and unsubstituted flavone or isoflavone glycoside derivatives of the formula [A 1 -C(═O)O] m —[X—O-Z]—[O—C(═O)-A 2 ] n , wherein [X—O-Z] represents a flavone or isoflavone glycoside structure, particularly a naringin residue, X is a flavone or isoflavone corresponding to formula (IIa) or formula (IIb): wherein the flavone or isoflavone residue is substituted one or more times and/or reduced one or more times; Z represents a mono-, di- or polysaccharide, which is acetally-bound at the benzopyran group to X and ester-substituted by —O—C(═O)-A 2 ; [A 1 -C(═O)] is an acyl group on the flavone or isoflavone; A 1 and A 2 independently, represent a polyunsaturated C 15-26 alkenyl group containing at least four isolated and/or at least two conjugated double bonds, or an arylaliphatic radical with 1-to-4 methylene groups between the ester group and the aromatic ring; [C(═O)A 2 ] is an acyl group; n is an integer other than 0; m is an integer, including 0; and R1, R2 and R are hydroxyl groups or hydrogen atoms.