3-溴-呋喃-2-羧酸甲基酰胺 | 816418-32-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 3-溴-呋喃-2-羧酸甲基酰胺
• 英文名称: 3-bromofuran-2-carboxylic acid methylamide
• 英文别名: N-Methyl-3-bromofuran-2-carboxamide；3-bromo-N-methylfuran-2-carboxamide
• CAS: 816418-32-3
• 化学式: C₆H₆BrNO₂
• 分子量: 204.023
• InChiKey: RGFCSBABKZXBEH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  42.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-碘代甲苯 、 3-溴-呋喃-2-羧酸甲基酰胺 在 降冰片烯 palladium diacetate 、 三(2-呋喃基)膦 、 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以82%的产率得到5,6-dimethyl-5H-furo[2,3-c]quinolin-4-one
  参考文献：
  名称：

  Synthesis of 6-Phenanthridinones and Their Heterocyclic Analogues through Palladium-Catalyzed Sequential Aryl−Aryl and N-Aryl Coupling

  摘要：

  6-Phenanthridinones and their heterocyclic analogues were synthesized through a one-pot procedure based on consecutive Pd-catalyzed aryl-aryl and N-aryl coupling from iodoarenes ortho-substituted by electron-releasing substituents and amides of o-bromoarene- and heteroarenecarboxylic acids.

  DOI：

  10.1021/ol0479949
• 作为产物：
  描述：

  3-溴-2-呋喃甲酸 在 磺酰氯 、 N,N-二甲基甲酰胺 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 生成 3-溴-呋喃-2-羧酸甲基酰胺
  参考文献：
  名称：

  Synthesis of 6-Phenanthridinones and Their Heterocyclic Analogues through Palladium-Catalyzed Sequential Aryl−Aryl and N-Aryl Coupling

  摘要：

  6-Phenanthridinones and their heterocyclic analogues were synthesized through a one-pot procedure based on consecutive Pd-catalyzed aryl-aryl and N-aryl coupling from iodoarenes ortho-substituted by electron-releasing substituents and amides of o-bromoarene- and heteroarenecarboxylic acids.

  DOI：

  10.1021/ol0479949

文献信息

• AMIDE COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL MICROBICIDE COMPRISING THE COMPOUND AND THE SALT, AND METHOD FOR USING THE AGRICULTURAL AND HORTICULTURAL MICROBICIDE
  申请人：Nihon Nohyaku Co., Ltd.

  公开号：US20210000111A1

  公开（公告）日：2021-01-07

  An amide compound represented by the general formula [I]: or a salt thereof, an agricultural and horticultural microbicide comprising the compound or the salt as an active ingredient, and a method for using the agricultural and horticultural microbicide.

  由一般式[I]表示的酰胺化合物或其盐，包含该化合物或盐作为活性成分的农业和园艺微生物杀菌剂，以及使用该农业和园艺微生物杀菌剂的方法。
• Amide compound or salt thereof, agricultural and horticultural microbicide comprising the compound and the salt, and method for using the agricultural and horticultural microbicide
  申请人：Nihon Nohyaku Co., Ltd.

  公开号：US11324219B2

  公开（公告）日：2022-05-10

  An amide compound represented by the general formula [I]: or a salt thereof, an agricultural and horticultural microbicide comprising the compound or the salt as an active ingredient, and a method for using the agricultural and horticultural microbicide.

  通式 [I] 所代表的酰胺化合物： 或其盐，一种包含该化合物或其盐作为活性成分的农业和园艺杀微生物剂，以及一种使用该农业和园艺杀微生物剂的方法。