N-{2-[3-(4-chlorophenyl)-2-(2-methoxyphenyl)-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-5-yl]ethaneyl}ethanamide | 1566591-79-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-{2-[3-(4-chlorophenyl)-2-(2-methoxyphenyl)-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-5-yl]ethaneyl}ethanamide
• 英文别名: N-{2-[3-(4-chlorophenyl)-2-(2-methoxyphenyl)-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-5-yl]ethyl}ethaneamide；N-{2-[3-(4-chlorophenyl)-2-(2-methoxyphenyl)-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-5-yl]ethyl}ethanamide；N-{2-[3-(4-chlorophenyl)-2-(2-methoxyphenyl)-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-5-yl]ethyl}acetamide；N-[2-[3-(4-chlorophenyl)-2-(2-methoxyphenyl)-5,6-dihydro-4H-cyclopenta[c]pyrazol-5-yl]ethyl]acetamide
• CAS: 1566591-79-4
• 化学式: C₂₃H₂₄ClN₃O₂
• 分子量: 409.915
• InChiKey: UJNSHINQNUFZLU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  56.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• CYCLOPENTYLPYRAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS
  申请人：Janssen Pharmaceutica NV

  公开号：US20140051660A1

  公开（公告）日：2014-02-20

  Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein R 1 , R 2 , R 3 , Q, and G are defined herein.
• US8853418B2
  申请人：——

  公开号：US8853418B2

  公开（公告）日：2014-10-07