Bioinspired Construction of a Spirocyclohexadienone Moiety via Sodium Nitrite Catalyzed Aerobic Intramolecular Oxidative Phenol Coupling
摘要:
An efficient and green intramolecular oxidative phenol coupling for the direct construction of spirocyclohexadienones has been developed, which uses environment-friendly sodium nitrite as the catalyst and oxygen in the air as the terminal oxidant. Hydroxy-containing substituted phenanthrenes and dibenzoazepines could be easily obtained from the dienone-phenol rearrangement.