3-Acetaminomethylpyrazol | 90030-58-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3-Acetaminomethylpyrazol
• 英文别名: N-(1(2)H-pyrazol-3-ylmethyl)-acetamide；N-[(1H-pyrazol-3-yl)methyl]acetamide；N-(1H-pyrazol-5-ylmethyl)acetamide
• CAS: 90030-58-3
• 化学式: C₆H₉N₃O
• 分子量: 139.157
• InChiKey: REXHZYNNJKUBPO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  57.8
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Non-Nucleoside Reverse Transcriptase Inhibitors
  申请人：Wolkenberg Scott E.

  公开号：US20100222322A1

  公开（公告）日：2010-09-02

  Indole compounds of Formula (I) are HIV reverse transcriptase inhibitors, wherein R 1 , R 2 , R 3 , R 4 and R 5 are defined herein. The compounds of Formula (I) and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

  公式（I）的吲哚化合物是HIV反转录酶抑制剂，其中R1、R2、R3、R4和R5的定义在此处。公式（I）的化合物及其药学上可接受的盐在抑制HIV反转录酶、预防和治疗HIV感染以及预防、延迟发病和治疗艾滋病方面是有用的。这些化合物及其盐可以作为药物组成部分，可选择与其他抗病毒药物、免疫调节剂、抗生素或疫苗组合使用。
• TROPOMYOSIN-RELATED KINASE INHIBITORS
  申请人：PFIZER INC

  公开号：US20150322043A1

  公开（公告）日：2015-11-12

  The present invention relates to compounds of Formula I and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine, in particular as TrkA antagonists.

  本发明涉及公式I化合物及其药学上可接受的盐，其中取代基如本文所述，并且它们在医学上的应用，特别是作为TrkA拮抗剂。
• METHOD AND VEHICLE FOR APPLYING AN AGROCHEMICAL MIXTURE TO A WORKING AREA OF A FIELD
  申请人：BASF SE

  公开号：EP3072376A2

  公开（公告）日：2016-09-28

  The present invention relates to a method for applying an agrochemical mixture to a working area (2) of a field (1) using a vehicle (3) moving on the field (1). Thereby, a solid fertilizer (6) is spread on the working area (2) using a fertilizer spreading device (4) mounted on the vehicle (3; 3a) and a liquid fertilizer additive (7) is sprayed on the working area (2) using a field sprayer (5), mounted on the vehicle (3) separately from the fertilizer spreading device (4). Therein, the liquid fertilizer additive (7) is prevented from coming into contact with surfaces of the fertilizer spreading device (4), which also come into contact with the solid fertilizer (6). Moreover, the invention relates to a vehicle (3) for applying an agrochemical mixture to a working area (2) of a field (1) while moving on the field (1).

  本发明涉及一种使用在田地（1）上行驶的车辆（3）向田地（1）的作业区（2）施用农用化学品混合物的方法。因此，使用安装在车辆（3；3a）上的肥料撒布装置（4）将固体肥料（6）撒布在作业区（2）上，并使用安装在车辆（3）上与肥料撒布装置（4）分开的田间喷雾器（5）将液体肥料添加剂（7）喷洒在作业区（2）上。这样，液体肥料添加剂（7）就不会与撒肥装置（4）的表面接触，而撒肥装置（4）的表面也会与固体肥料（6）接触。此外，本发明还涉及一种车辆 (3)，用于在田地 (1) 上移动时向田地 (1) 的作业区 (2) 施用农用化学品混合物。
• Method and vehicle for applying an agrochemical mixture to a working area of a field
  申请人：BASF SE

  公开号：US10485162B2

  公开（公告）日：2019-11-26

  A method for applying an agrochemical mixture to a working area of a field using a vehicle moving on the field is described. Thereby, a solid fertilizer is spread on the working area using a fertilizer spreading device mounted on the vehicle and a liquid fertilizer additive is sprayed on the working area using a field sprayer, mounted on the vehicle separately from the fertilizer spreading device. Therein, the liquid fertilizer additive is prevented from coming into contact with surfaces of the fertilizer spreading device, which also come into contact with the solid fertilizer. Moreover, a vehicle for applying an agrochemical mixture to a working area of a field while moving on the field is also described.

  描述了一种利用在田间行驶的车辆在田间作业区施用农用化学品混合物的方法。通过这种方法，使用安装在车辆上的肥料撒布装置将固体肥料撒布到作业区，并使用安装在车辆上与肥料撒布装置分开的田间喷雾器将液体肥料添加剂喷洒到作业区。这样，液体肥料添加剂就不会与撒肥装置的表面接触，而撒肥装置的表面也会与固体肥料接触。此外，还介绍了一种在田间移动时向田间作业区施用农用化学品混合物的车辆。
• Pyrazole compounds as nitrification inhibitors
  申请人：BASF SE

  公开号：US10556844B2

  公开（公告）日：2020-02-11

  Pyrazole derivatives as nitrification inhibitors are described herein.

  本文介绍了作为硝化抑制剂的吡唑衍生物。