(S)-diethyl(3-{2-[3-(4-methoxyphenyl)[1,2,4]oxadiazol-5-yl]pyrrolidine-1-sulfonyl}propyl)amine | 957068-36-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: (S)-diethyl(3-{2-[3-(4-methoxyphenyl)[1,2,4]oxadiazol-5-yl]pyrrolidine-1-sulfonyl}propyl)amine
• 英文别名: N,N-diethyl-3-[(2S)-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl]sulfonylpropan-1-amine
• CAS: 957068-36-9
• 化学式: C₂₀H₃₀N₄O₄S
• 分子量: 422.549
• InChiKey: NFIRFLZZOLPEBC-SFHVURJKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  29
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  97.2
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• METHODS OF TREATING MILD BRAIN INJURY
  申请人：Oxeia Biopharmaceuticals Inc.

  公开号：EP3182992A1

  公开（公告）日：2017-06-28
• [EN] METHODS OF TREATING MILD BRAIN INJURY<br/>[FR] MÉTHODES DE TRAITEMENT D'UNE LÉSION CÉRÉBRALE LÉGÈRE
  申请人：OXEIA BIOPHARMACEUTICALS INC

  公开号：WO2016028826A1

  公开（公告）日：2016-02-25

  The present disclosure provides methods for treating mild brain injury and other neurological disorders in a subject in need thereof, comprising administering to the subject an effective amount of a compound comprising a ghrelin or ghrelin variant. This invention provides for methods for treating a mild brain injury or concussion in a patient wherein said method comprises administering to the subject in need thereof suffering from said mild brain injury or concussion an effective amount of a ghrelin variant or a composition comprising a ghrelin variant so as to treat said mild brain injury or concussion.