2-(2-methoxyphenyl)-5',5'-dimethyl-3-(6-methylpyridin-3-yl)-2,6-dihydro-4H-spiro[cyclopenta[c]pyrazole-5,2'-[1,3]dioxane] | 1566592-73-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-(2-methoxyphenyl)-5',5'-dimethyl-3-(6-methylpyridin-3-yl)-2,6-dihydro-4H-spiro[cyclopenta[c]pyrazole-5,2'-[1,3]dioxane]
• 英文别名: 2'-(2-Methoxyphenyl)-5,5-dimethyl-3'-(6-methylpyridin-3-yl)spiro[1,3-dioxane-2,5'-4,6-dihydrocyclopenta[c]pyrazole]
• CAS: 1566592-73-1
• 化学式: C₂₄H₂₇N₃O₃
• 分子量: 405.497
• InChiKey: JLFGWRPODYODLH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  30
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  58.4
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• CYCLOPENTYLPYRAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS
  申请人：Janssen Pharmaceutica NV

  公开号：US20140051660A1

  公开（公告）日：2014-02-20

  Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein R 1 , R 2 , R 3 , Q, and G are defined herein.
• US8853418B2
  申请人：——

  公开号：US8853418B2

  公开（公告）日：2014-10-07