2-amino-2-{2-[4-(1-hexyl-1H-pyrazol-4-yl)phenyl]ethyl}propane-1,3-diol | 845550-37-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-amino-2-{2-[4-(1-hexyl-1H-pyrazol-4-yl)phenyl]ethyl}propane-1,3-diol
• 英文别名: 2-Amino-2-[2-[4-(1-hexylpyrazol-4-yl)phenyl]ethyl]propane-1,3-diol
• CAS: 845550-37-0
• 化学式: C₂₀H₃₁N₃O₂
• 分子量: 345.485
• InChiKey: DWHAAEIDNNRICP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  25
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  84.3
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• [EN] BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY<br/>[FR] COMPOSE BI-ARYLE PRESENTANT UNE ACTIVITE IMMUNOSUPPRESSIVE
  申请人：MITSUBISHI PHARMA CORP

  公开号：WO2005014525A2

  公开（公告）日：2005-02-17

  The invention is directed to a bi-aryl compound having a unique immunomodulating activity, a process for a preparation thereof, a pharmaceutical composition containing the same, and a method of preventing or treating disorders or diseases mediated by T lymphocytes by administering the compound to a subject in need of treatment.