3-甲基十七烷酸 | 60787-51-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 3-甲基十七烷酸
• 英文名称: 3-Methylheptadecansaeure
• 英文别名: beta-methylheptadecanoic acid；3-Methylheptadecanoic acid
• CAS: 60787-51-1
• 化学式: C₁₈H₃₆O₂
• 分子量: 284.483
• InChiKey: WUMIFWUKSVCEOW-UHFFFAOYSA-N

物化性质

• 沸点：
  369.53°C (estimate)
• 密度：
  0.8833 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  20
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-溴-2-甲基十六烷 生成 3-甲基十七烷酸
  参考文献：
  名称：

  ELMALEH, D. R.;LIVNI, E.;STRAUSS, H. W.;BROWNELL, G. L., J. LABELLED COMPOUNDS AND RADIOPHARM., 1984, 21, N 11-12, 1203-1204

  摘要：

  DOI：

文献信息

• Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid
  申请人：——

  公开号：US20040253177A1

  公开（公告）日：2004-12-16

  The present invention relates to novel modified fatty acid analogs, where a positron or gamma-emitting label is placed at a position on a fatty acid backbone and an organic substituent is substituted at the 2,3; 3,4; 4,5; 5,6 and other sequence positions of a fatty acid backbone. These novel fatty acid analogs are designed to enter the tissues of interest by the same long chain fatty acid carrier mechanism as natural fatty acids, however, functional substituents in the 2,3; 3,4; 4,5; 5,6 and other sequence positions, block the catabolic pathway, thus trapping these analogs in a virtually unmodified form in the tissues of interest.

  本发明涉及新型的改性脂肪酸类似物，其中在脂肪酸骨架的某个位置放置一个正电子或伽马发射标签，并且在脂肪酸骨架的2,3; 3,4; 4,5; 5,6等序列位置上用有机取代基进行取代。这些新型的脂肪酸类似物旨在通过天然长链脂肪酸载体机制进入感兴趣的组织，然而，2,3; 3,4; 4,5; 5,6等序列位置的功能性取代基阻断了分解代谢途径，从而将这些类似物以几乎未修改的形式陷阱在感兴趣的组织中。
• METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID
  申请人：Elmaleh David R.

  公开号：US20130052129A1

  公开（公告）日：2013-02-28

  The present invention relates to novel modified fatty acid analogs, where a positron or gamma-emitting label is placed at a position on a fatty acid backbone and an organic substituent is substituted at the 2,3; 3,4; 4,5; 5,6 and other sequence positions of a fatty acid backbone. These novel fatty acid analogs are designed to enter the tissues of interest by the same long chain fatty acid carrier mechanism as natural fatty acids, however, functional substituents in the 2,3; 3,4; 4,5; 5,6 and other sequence positions, block the catabolic pathway, thus trapping these analogs in a virtually unmodified form in the tissues of interest.

  本发明涉及一种新型的改性脂肪酸类似物，其中在脂肪酸骨架的一个位置放置正电子或伽马发射标签，并在脂肪酸骨架的2,3; 3,4; 4,5; 5,6和其他序列位置上替换有机取代基。这些新型脂肪酸类似物被设计为通过与天然脂肪酸相同的长链脂肪酸载体机制进入感兴趣的组织，但是，在2,3; 3,4; 4,5; 5,6和其他序列位置上的功能性取代基会阻止分解途径，从而在感兴趣的组织中将这些类似物困在几乎未经修改的形式中。
• Lipid metabolic and signalling pathways in the epidermis
  申请人：Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.

  公开号：EP1626089A1

  公开（公告）日：2006-02-15

  The present invention relates to the field of genes isolated from Arabidopsis that code for enzymes that are involved in ω-oxidation of very long chain fatty acids, particularly, in conversion of ω-hydroxy fatty acid to fatty aldehyde. The invention also includes methods of producing transgenic plants with an altered fatty acid composition. Furthermore, the present invention relates to assays making use of these enzymes as herbicide targets to identify inhibitors of said enzymes, thereby providing herbicidally active compounds.

  本发明涉及从拟南芥中分离的基因领域，这些基因编码参与超长链脂肪酸ω-氧化的酶，特别是参与将ω-羟基脂肪酸转化为脂肪醛的酶。本发明还包括生产脂肪酸组成改变的转基因植物的方法。此外，本发明还涉及利用这些酶作为除草剂靶标的检测方法，以鉴定所述酶的抑制剂，从而提供除草活性化合物。
• EP1622602A4
  申请人：——

  公开号：EP1622602A4

  公开（公告）日：2006-06-21
• LIPID METABOLIC AND SIGNALLING PATHWAYS IN THE EPIDERMIS
  申请人：Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.

  公开号：EP1786909A1

  公开（公告）日：2007-05-23