N-Ethyl-N-(phenylmethyl)-1H-pyrazole-4-carboxamide | 1153208-27-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-Ethyl-N-(phenylmethyl)-1H-pyrazole-4-carboxamide
• 英文别名: N-benzyl-N-ethyl-1H-pyrazole-4-carboxamide
• CAS: 1153208-27-5
• 化学式: C₁₃H₁₅N₃O
• 分子量: 229.28
• InChiKey: RWAHAIYSRAUGON-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  49
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] SUBSTITUTED 2-(1H-PYRAZOL-1-YL)-BENZOTHIAZOLE COMPOUNDS<br/>[FR] COMPOSÉS 2-(1H-PYRAZOL-1-YL)-BENZOTHIAZOLE SUBSTITUÉS
  申请人：BAYER PHARMA AG

  公开号：WO2017063966A1

  公开（公告）日：2017-04-20

  The present invention relates to substituted 2-(pyrazol-1-yl)-benzothiazole compounds of general formula (I) in which R1, R8, R9 and R10 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.