3-(5-Methyl-4H-1,2,4-triazol-3-yl)aniline hydrate | 1609406-60-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3-(5-Methyl-4H-1,2,4-triazol-3-yl)aniline hydrate
• 英文别名: 3-(5-methyl-1H-1,2,4-triazol-3-yl)aniline;hydrate
• CAS: 1609406-60-1
• 化学式: C9H12N4O
• 分子量: 192.22
• InChiKey: WNNZJFVNICBRSG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.54
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  68.6
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• 2-Amino-1-phenyl-pyrrolo[3,2-b]quinoxaline-3-carboxamide derivates
  申请人：Universität Zürich

  公开号：EP2924039A1

  公开（公告）日：2015-09-30

  The invention relates to compound characterized by a general formula (1), wherein n of R1n is 0, 1, 2, 3 or 4, in particular n of R1n is 0 or 1, and each R1 independently from any other R1 is C1-C3 alkyl, C1-C3 haloalkyl or C1-C3 alkoxy, and DA is a Donor-Acceptor group. The invention relates further to a compound or a pharmaceutical preparation for use in a method for treatment of cancer or intraocular neovascular syndromes.

  该发明涉及一种具有一般式(1)的化合物，其中R1n的n为0、1、2、3或4，特别是R1n的n为0或1，每个R1独立于其他R1，为C1-C3烷基、C1-C3卤代烷基或C1-C3烷氧基，DA为给体-受体基团。该发明还涉及一种化合物或药物制剂，用于治疗癌症或眼内新生血管综合征的方法。
• [EN] 2-AMINO-1-PHENYL-PYRROLO[3,2-B]QUINOXALINE-3-CARBOXAMIDE DERIVATES<br/>[FR] DÉRIVÉS 2-AMINO-1-PHÉNYL-PYRROLO[3,2-B]QUINOXALINE-3-CARBOXAMIDE
  申请人：UNIV ZUERICH

  公开号：WO2015144926A1

  公开（公告）日：2015-10-01

  The invention relates to compound characterized by a general formula (1), wherein n of R1n is 0, 1, 2, 3 or 4, in particular n of R1n is 0 or 1, and each R1 independently from any other R1 is C1-C3 alkyl, C1-C3 haloalkyl or C1-C3 alkoxy, and DA is a Donor-Acceptor group. The invention relates further to a compound or a pharmaceutical preparation for use in a method for treatment of cancer or intraocular neovascular syndromes.