Enantio- and Diastereoselective Iodocyclopropanation of Allylic Alcohols by Using a Substituted Zinc Carbenoid
作者:Louis-Philippe B. Beaulieu、Lucie E. Zimmer、André B. Charette
DOI:10.1002/chem.200902228
日期:2009.11.9
(Zinc)redible! 2,3‐Disubstituted and 2,3‐trisubstituted iodocyclopropanes can be accessed in enantiomerically enriched form by using the enantioselective Simmons–Smith iodocyclopropanation of allylicalcohols in the presence of the stoichiometric dioxaborolane chiral ligand. These iodocyclopropanes serve as versatile chiral building blocks towards highly functionalized 1,2,3‐trisubstituted cyclopropanes