dimethylaminoethanethiolato(thiopropionato)bismuth | 790224-56-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: dimethylaminoethanethiolato(thiopropionato)bismuth
• CAS: 790224-56-5
• 化学式: C₇H₁₄BiNO₂S₂
• 分子量: 417.306
• InChiKey: GEBRNXUYSXJXLL-UHFFFAOYSA-K

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  卡普他明 、 potassium dichloro(thiopropionato)bismuth 以 乙醇 为溶剂， 以56%的产率得到dimethylaminoethanethiolato(thiopropionato)bismuth
  参考文献：
  名称：

  Identification, Isolation, and Characterization of Cysteinate and Thiolactate Complexes of Bismuth

  摘要：

  Although bismuth compounds have been used in medicine for over 200 years, chemical characterization of complexes involving biological molecules is minimal and mechanisms of bioactivity are ill-defined. The thiophilic nature of bismuth implicates sulfur centers as likely sites for interaction, and we have exploited this feature to identify, isolate, and characterize complexes of bismuth with thiolate-carboxylate bifunctional ligands including the amino acid L-cysteine. The solid-state structures of potassium dichloro(thiopropionato)bismuth (K[1d]), dimethylamino-ethanethiolato(thiopropionato)bismuth (4), and dinitrato(cysteinato)bismuthphenanthroline [5(phen)] are compared with data from electrospray ionization mass spectrometry (ESI-MS). ESI-MS is applied to reactions of 303 or Bi(NO3)(3) with mercaptosuccinic, malic, and succinic acids to illustrate the general observation of 1:1 and 1:2 complexes.

  DOI：

  10.1021/ic049594n