2-(5-methyl-4-phenyl-1H-imidazol-2-yl)benzoic acid | 824395-46-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-(5-methyl-4-phenyl-1H-imidazol-2-yl)benzoic acid
• CAS: 824395-46-2
• 化学式: C₁₇H₁₄N₂O₂
• 分子量: 278.3
• InChiKey: HAQYMOGJMNIWFQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  66
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Asymmetric benzimidazoles and related compounds as potassium channel modulators
  申请人：Wang Xiaodong

  公开号：US20050038067A1

  公开（公告）日：2005-02-17

  The present invention provides a genus of asymmetric benzimidazole compounds, methods and pharmaceutical compositions that are useful as modulators of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.

  本发明提供了一种可用作钾离子通道调节剂的不对称苯并咪唑化合物、方法和药物组合物。本发明的化合物可用于治疗和诊断方法。
• US7777051B2
  申请人：——

  公开号：US7777051B2

  公开（公告）日：2010-08-17
• [EN] ASYMMETRIC BENZIMIDAZOLES AND RELATED COMPOUNDS AS POTASSIUM CHANNEL MODULATORS<br/>[FR] BENZIMIDAZOLES ASYMETRIQUES ET COMPOSES LIES TELS QUE DES MODULATEURS DE CANAL A POTASSIUM
  申请人：ICAGEN INC

  公开号：WO2005002503A2

  公开（公告）日：2005-01-13

  The present invention provides a genus of asymmetric benzimidazole compounds, methods and pharmaceutical compositions that are useful as modulators of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.